Date published: 2025-10-10

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METTL1 Activators

The chemicals categorized as METTL1 Activators primarily operate within the framework of methylation reactions and the cellular environment, exerting their influence indirectly on METTL1's activity. Central to this list is SAM, a universal methyl donor that stands fundamental for the operation of methyltransferases like METTL1. Its availability and cellular levels are vital for ensuring METTL1's function, with related molecules like Vitamin B12 and Folic Acid supporting the methyl cycle and facilitating SAM production, subsequently backing METTL1's activity.

Furthermore, the list encompasses chemicals that recalibrate the broader cellular methylation panorama. Agents like Zebularine and 5-Aza-2'-deoxycytidine, known as DNA methyltransferase inhibitors, alter the methylation state of the genome and can, in turn, influence METTL1's activity in that changed context. Likewise, natural compounds such as EGCG, Genistein, Quercetin, Curcumin, and Resveratrol are recognized for their ability to modulate methylation processes in cells. Their presence can shape the methylation dynamics, offering indirect modulation to enzymes like METTL1.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ademetionine

29908-03-0sc-278677
sc-278677A
100 mg
1 g
$180.00
$655.00
2
(1)

Universal methyl donor, essential for the function of methyltransferases, including METTL1.

Vitamin B12

68-19-9sc-296695
sc-296695A
sc-296695B
sc-296695C
sc-296695D
sc-296695E
100 mg
1 g
5 g
25 g
100 g
1 kg
$39.00
$55.00
$204.00
$877.00
$3414.00
$9180.00
2
(1)

Involved in methylation reactions; can support METTL1 activity indirectly through methyl cycle.

Folic Acid

59-30-3sc-204758
10 g
$72.00
2
(1)

Facilitates the production of SAM, indirectly promoting METTL1 activity.

Zebularine

3690-10-6sc-203315
sc-203315A
sc-203315B
10 mg
25 mg
100 mg
$126.00
$278.00
$984.00
3
(1)

DNA methyltransferase inhibitor; may indirectly affect METTL1 activity by influencing cellular methylation landscape.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

Can modulate methylation processes, potentially influencing METTL1 activity.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$88.00
$208.00
24
(2)

HDAC inhibitor; alters methylation landscape, potentially affecting METTL1 activity.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

DNA methyltransferase inhibitor; might influence the cellular environment and METTL1's activity.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Influences DNA methylation, potentially indirectly modulating METTL1 activity.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Known to modulate methylation processes; can affect METTL1 indirectly.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Influences various methylation pathways, potentially indirectly supporting METTL1 activity.