The chemicals categorized as METTL1 Activators primarily operate within the framework of methylation reactions and the cellular environment, exerting their influence indirectly on METTL1's activity. Central to this list is SAM, a universal methyl donor that stands fundamental for the operation of methyltransferases like METTL1. Its availability and cellular levels are vital for ensuring METTL1's function, with related molecules like Vitamin B12 and Folic Acid supporting the methyl cycle and facilitating SAM production, subsequently backing METTL1's activity.
Furthermore, the list encompasses chemicals that recalibrate the broader cellular methylation panorama. Agents like Zebularine and 5-Aza-2'-deoxycytidine, known as DNA methyltransferase inhibitors, alter the methylation state of the genome and can, in turn, influence METTL1's activity in that changed context. Likewise, natural compounds such as EGCG, Genistein, Quercetin, Curcumin, and Resveratrol are recognized for their ability to modulate methylation processes in cells. Their presence can shape the methylation dynamics, offering indirect modulation to enzymes like METTL1.
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Items 1 to 10 of 11 total
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
Universal methyl donor, essential for the function of methyltransferases, including METTL1. | ||||||
Vitamin B12 | 68-19-9 | sc-296695 sc-296695A sc-296695B sc-296695C sc-296695D sc-296695E | 100 mg 1 g 5 g 25 g 100 g 1 kg | $39.00 $55.00 $204.00 $877.00 $3414.00 $9180.00 | 2 | |
Involved in methylation reactions; can support METTL1 activity indirectly through methyl cycle. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Facilitates the production of SAM, indirectly promoting METTL1 activity. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $126.00 $278.00 $984.00 | 3 | |
DNA methyltransferase inhibitor; may indirectly affect METTL1 activity by influencing cellular methylation landscape. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Can modulate methylation processes, potentially influencing METTL1 activity. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
HDAC inhibitor; alters methylation landscape, potentially affecting METTL1 activity. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
DNA methyltransferase inhibitor; might influence the cellular environment and METTL1's activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Influences DNA methylation, potentially indirectly modulating METTL1 activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Known to modulate methylation processes; can affect METTL1 indirectly. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Influences various methylation pathways, potentially indirectly supporting METTL1 activity. |