MDH2 Inhibitors
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
K252c | 85753-43-1 | sc-24011 sc-24011A | 1 mg 5 mg | $87.00 $374.00 | 3 | |
K252c acts as a potent modulator of MDH2, characterized by its ability to form stable complexes with the enzyme. This compound engages in specific hydrogen bonding and hydrophobic interactions, which significantly influence the enzyme's conformational dynamics. By altering the enzyme's active site accessibility, K252c effectively shifts the equilibrium of metabolic pathways. Its unique physicochemical properties enhance solubility, promoting efficient cellular uptake and interaction with target proteins. | ||||||
Oxaloacetic Acid | 328-42-7 | sc-279934 sc-279934A sc-279934B | 25 g 100 g 1 kg | $306.00 $963.00 $7980.00 | 1 | |
Competes with oxaloacetate, potentially inhibiting MDH2 by blocking its active site. | ||||||
3-Nitropropionic acid | 504-88-1 | sc-214148 sc-214148A | 1 g 10 g | $82.00 $459.00 | ||
Inhibits mitochondrial enzymes; could disrupt MDH2 activity by interfering with electron transport. | ||||||
Gossypol | 303-45-7 | sc-200501 sc-200501A | 25 mg 100 mg | $116.00 $230.00 | 12 | |
Aldehyde groups in gossypol can potentially bind to the NAD+ binding site of MDH2, inhibiting its activity. | ||||||
Phenylglyoxal monohydrate | 1074-12-0 | sc-258007 sc-258007A | 5 g 25 g | $174.00 $522.00 | ||
Reacts with arginine residues; could modify MDH2 active site and inhibit its function. | ||||||
2-Thenoyltrifluoroacetone | 326-91-0 | sc-251801 | 5 g | $37.00 | 1 | |
Chelates divalent metal ions; could disrupt MDH2 activity by removing essential cofactors. | ||||||
Vitamin K3 | 58-27-5 | sc-205990B sc-205990 sc-205990A sc-205990C sc-205990D | 5 g 10 g 25 g 100 g 500 g | $26.00 $36.00 $47.00 $136.00 $455.00 | 3 | |
Interferes with electron transport chain; might indirectly affect MDH2 function. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $69.00 $214.00 $796.00 $1918.00 | 19 | |
Modifies cysteine residues; could inhibit MDH2 by altering its active site conformation. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $108.00 $780.00 | 3 | |
Interacts with thiol groups; might inhibit MDH2 by binding to its active site. | ||||||
Fumaric acid | 110-17-8 | sc-250031 sc-250031A sc-250031B sc-250031C | 25 g 100 g 500 g 2.5 kg | $43.00 $57.00 $114.00 $228.00 | ||
Might inhibit MDH2 by competing with its natural substrates in the Krebs cycle. | ||||||