Date published: 2025-11-21

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MD-2 Antibodies

Santa Cruz Biotechnology offers a broad range of MD-2 monoclonal antibodies for research focused on understanding immune response mechanisms. MD-2 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MD-2 is a critical component of the Toll-like receptor 4 (TLR4) complex, playing a vital role in the recognition of lipopolysaccharides (LPS) from Gram-negative bacteria. This interaction is essential for initiating innate immune responses and modulating inflammation. Understanding the function of MD-2 is crucial for developing therapeutic strategies against various infectious diseases and inflammatory conditions. MD-2 monoclonal antibodies enable researchers to explore cellular signaling pathways involved in immune response regulation. Investigating MD-2's role in TLR4 signaling can reveal new insights into inflammatory disease mechanisms. Research utilizing MD-2 monoclonal antibodies contributes to advancing immunology studies and developing potential therapeutic interventions. Santa Cruz Biotechnology monoclonal antibodies support the scientific community in advancing our understanding of immune system regulation and disease pathogenesis.

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MD-2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MD-2 Antibody (J-12B)

sc-80183mouse IgG1 κFL (h)WB, ELISAh
11
(3)

MD-2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MD-2 CRISPR/Cas9 KO Plasmid (h)

sc-417315hGene KnockoutGFP0
(0)

MD-2 HDR Plasmid (h)

sc-417315-HDRhHomology Directed RepairPuromycin0
(0)

MD-2 Double Nickase Plasmid (h)

sc-417315-NIChGene KnockoutPuromycin0
(0)

MD-2 Double Nickase Plasmid (h2)

sc-417315-NIC-2hGene KnockoutPuromycin0
(0)

MD-2 CRISPR/Cas9 KO Plasmid (m)

sc-421507mGene KnockoutGFP0
(0)

MD-2 HDR Plasmid (m)

sc-421507-HDRmHomology Directed RepairPuromycin0
(0)

MD-2 Double Nickase Plasmid (m)

sc-421507-NICmGene KnockoutPuromycin0
(0)

MD-2 Double Nickase Plasmid (m2)

sc-421507-NIC-2mGene KnockoutPuromycin0
(0)

MD-2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MD-2 CRISPR Activation Plasmid (h)

sc-417315-ACThGene ActivationPuro, Blast, Hygro0
(0)

MD-2 CRISPR Activation Plasmid (h2)

sc-417315-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MD-2 Lentiviral Activation Particles (h)

sc-417315-LAChGene ActivationPuro, Blast, Hygro0
(0)

MD-2 Lentiviral Activation Particles (h2)

sc-417315-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MD-2 CRISPR Activation Plasmid (m)

sc-421507-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MD-2 CRISPR Activation Plasmid (m2)

sc-421507-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MD-2 Lentiviral Activation Particles (m)

sc-421507-LACmGene ActivationPuro, Blast, Hygro0
(0)

MD-2 Lentiviral Activation Particles (m2)

sc-421507-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MD-2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MD-2 siRNA (h)

sc-35889hGene SilencingN/A
1
(0)

MD-2 shRNA Plasmid (h)

sc-35889-SHhGene SilencingPuromycin
1
(0)

MD-2 shRNA (h) Lentiviral Particles

sc-35889-VhGene SilencingPuromycin
1
(0)

MD-2 siRNA (m)

sc-35890mGene SilencingN/A0
(0)

MD-2 shRNA Plasmid (m)

sc-35890-SHmGene SilencingPuromycin0
(0)

MD-2 shRNA (m) Lentiviral Particles

sc-35890-VmGene SilencingPuromycin0
(0)