Date published: 2025-11-23

1-800-457-3801

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MARK CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. MARK gene silencers are available as MARK CRISPR/Cas9 Knockout plasmids and MARK Double Nickase Plasmids. MARK CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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MARK CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MARK1 CRISPR/Cas9 KO Plasmid (h)

sc-404508hGene KnockoutGFP0
(0)

MARK1 HDR Plasmid (h)

sc-404508-HDRhHomology Directed RepairPuromycin0
(0)

MARK1 Double Nickase Plasmid (h)

sc-404508-NIChGene KnockoutPuromycin0
(0)

MARK1 Double Nickase Plasmid (h2)

sc-404508-NIC-2hGene KnockoutPuromycin0
(0)

MARK1 CRISPR/Cas9 KO Plasmid (m)

sc-432657mGene KnockoutGFP0
(0)

MARK1 HDR Plasmid (m)

sc-432657-HDRmHomology Directed RepairPuromycin0
(0)

MARK1 Double Nickase Plasmid (m)

sc-432657-NICmGene KnockoutPuromycin0
(0)

MARK1 Double Nickase Plasmid (m2)

sc-432657-NIC-2mGene KnockoutPuromycin0
(0)

MARK2 CRISPR/Cas9 KO Plasmid (h)

sc-403714hGene KnockoutGFP
1
(0)

MARK2 HDR Plasmid (h)

sc-403714-HDRhHomology Directed RepairPuromycin
1
(0)

MARK2 Double Nickase Plasmid (h)

sc-403714-NIChGene KnockoutPuromycin
1
(0)

MARK2 Double Nickase Plasmid (h2)

sc-403714-NIC-2hGene KnockoutPuromycin
1
(0)

MARK2 CRISPR/Cas9 KO Plasmid (m)

sc-420164mGene KnockoutGFP0
(0)

MARK2 HDR Plasmid (m)

sc-420164-HDRmHomology Directed RepairPuromycin0
(0)

MARK2 Double Nickase Plasmid (m)

sc-420164-NICmGene KnockoutPuromycin0
(0)

MARK2 Double Nickase Plasmid (m2)

sc-420164-NIC-2mGene KnockoutPuromycin0
(0)

MARK3 CRISPR/Cas9 KO Plasmid (h)

sc-406362hGene KnockoutGFP0
(0)

MARK3 CRISPR/Cas9 KO Plasmid (h2)

sc-406362-KO-2hGene KnockoutGFP0
(0)

MARK3 HDR Plasmid (h2)

sc-406362-HDR-2hHomology Directed RepairPuromycin0
(0)

MARK3 Double Nickase Plasmid (h)

sc-406362-NIChGene KnockoutPuromycin0
(0)

MARK3 Double Nickase Plasmid (h2)

sc-406362-NIC-2hGene KnockoutPuromycin0
(0)

MARK3 CRISPR/Cas9 KO Plasmid (m)

sc-421560mGene KnockoutGFP0
(0)

MARK3 HDR Plasmid (m)

sc-421560-HDRmHomology Directed RepairPuromycin0
(0)

MARK3 Double Nickase Plasmid (m)

sc-421560-NICmGene KnockoutPuromycin0
(0)

MARK3 Double Nickase Plasmid (m2)

sc-421560-NIC-2mGene KnockoutPuromycin0
(0)

MARK4 CRISPR/Cas9 KO Plasmid (h)

sc-404386hGene KnockoutGFP
1
(0)

MARK4 HDR Plasmid (h)

sc-404386-HDRhHomology Directed RepairPuromycin
1
(0)

MARK4 Double Nickase Plasmid (h)

sc-404386-NIChGene KnockoutPuromycin
1
(0)

MARK4 Double Nickase Plasmid (h2)

sc-404386-NIC-2hGene KnockoutPuromycin
1
(0)

MARK4 CRISPR/Cas9 KO Plasmid (m)

sc-433214mGene KnockoutGFP0
(0)

MARK4 HDR Plasmid (m)

sc-433214-HDRmHomology Directed RepairPuromycin0
(0)

MARK4 Double Nickase Plasmid (m)

sc-433214-NICmGene KnockoutPuromycin0
(0)

MARK4 Double Nickase Plasmid (m2)

sc-433214-NIC-2mGene KnockoutPuromycin0
(0)

MARK CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MARK1 CRISPR Activation Plasmid (h)

sc-404508-ACThGene ActivationPuro, Blast, Hygro0
(0)

MARK1 CRISPR Activation Plasmid (h2)

sc-404508-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MARK1 Lentiviral Activation Particles (h)

sc-404508-LAChGene ActivationPuro, Blast, Hygro0
(0)

MARK1 Lentiviral Activation Particles (h2)

sc-404508-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MARK1 CRISPR Activation Plasmid (m)

sc-432657-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MARK1 CRISPR Activation Plasmid (m2)

sc-432657-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MARK1 Lentiviral Activation Particles (m)

sc-432657-LACmGene ActivationPuro, Blast, Hygro0
(0)

MARK1 Lentiviral Activation Particles (m2)

sc-432657-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MARK2 CRISPR Activation Plasmid (h)

sc-403714-ACThGene ActivationPuro, Blast, Hygro
1
(0)

MARK2 CRISPR Activation Plasmid (h2)

sc-403714-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

MARK2 Lentiviral Activation Particles (h)

sc-403714-LAChGene ActivationPuro, Blast, Hygro
1
(0)

MARK2 Lentiviral Activation Particles (h2)

sc-403714-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

MARK2 CRISPR Activation Plasmid (m)

sc-420164-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MARK2 CRISPR Activation Plasmid (m2)

sc-420164-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MARK2 Lentiviral Activation Particles (m)

sc-420164-LACmGene ActivationPuro, Blast, Hygro0
(0)

MARK2 Lentiviral Activation Particles (m2)

sc-420164-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MARK3 CRISPR Activation Plasmid (h)

sc-406362-ACThGene ActivationPuro, Blast, Hygro0
(0)

MARK3 CRISPR Activation Plasmid (h2)

sc-406362-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MARK3 Lentiviral Activation Particles (h)

sc-406362-LAChGene ActivationPuro, Blast, Hygro0
(0)

MARK3 Lentiviral Activation Particles (h2)

sc-406362-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MARK3 CRISPR Activation Plasmid (m)

sc-421560-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MARK3 CRISPR Activation Plasmid (m2)

sc-421560-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MARK3 Lentiviral Activation Particles (m)

sc-421560-LACmGene ActivationPuro, Blast, Hygro0
(0)

MARK3 Lentiviral Activation Particles (m2)

sc-421560-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MARK4 CRISPR Activation Plasmid (h)

sc-404386-ACThGene ActivationPuro, Blast, Hygro
1
(0)

MARK4 CRISPR Activation Plasmid (h2)

sc-404386-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

MARK4 Lentiviral Activation Particles (h)

sc-404386-LAChGene ActivationPuro, Blast, Hygro
1
(0)

MARK4 Lentiviral Activation Particles (h2)

sc-404386-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

MARK4 CRISPR Activation Plasmid (m)

sc-433214-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MARK4 CRISPR Activation Plasmid (m2)

sc-433214-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MARK4 Lentiviral Activation Particles (m)

sc-433214-LACmGene ActivationPuro, Blast, Hygro0
(0)

MARK4 Lentiviral Activation Particles (m2)

sc-433214-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)