Date published: 2026-5-4

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MAPKAPK-2 Substrates

Santa Cruz Biotechnology now offers a broad range of MAPKAPK-2 substrates for use in various applications. MAPKAPK-2, also known as mitogen-activated protein kinase-activated protein kinase 2, is an important enzyme that plays a crucial role in the cellular response to stress and inflammation. It is activated by p38 MAPK, a member of the MAPK family, which is involved in signaling pathways that control various cellular processes, including gene expression, cell differentiation, and apoptosis. MAPKAPK-2 substrates are essential tools in scientific research, enabling researchers to study the downstream effects of p38 MAPK activation and to investigate the specific biological processes regulated by MAPKAPK-2. These substrates are used to explore the phosphorylation events catalyzed by MAPKAPK-2, which can impact the function and activity of various target proteins involved in cellular responses to environmental stresses. Understanding how MAPKAPK-2 substrates interact with their targets allows scientists to dissect the signaling networks that modulate cellular function and to study the molecular mechanisms underlying stress response pathways. Additionally, MAPKAPK-2 substrates are valuable in the study of the interplay between different signaling pathways, contributing to an understanding of cellular signaling and regulation. View detailed information on our available MAPKAPK-2 substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

CREB1 (Ser 133)

sc-24520
0.5 mg/0.1 ml
$96.00
2
(0)

CREB-1 (Ser 133) functions as a pivotal regulator within the MAPK signaling cascade, specifically influencing transcriptional activity through phosphorylation. Its interaction with MAPKAPK-2 enhances the stability of the CREB protein, promoting its binding to DNA. This modification alters gene expression patterns, impacting cellular responses. The kinetics of this phosphorylation event are critical, as they dictate the temporal dynamics of signaling, ultimately shaping cellular fate decisions.