MALT1 Activators
MALT1 Activators belong to a specific category of molecules that play a crucial role in regulating cellular signaling pathways, particularly those involved in immune responses and inflammation. MALT1, which stands for Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1, is a key enzyme found in immune cells, including T cells and B cells. It is an essential component of the CARMA1-BCL10-MALT1 (CBM) complex, which functions as a signalosome in immune cells. This complex plays a pivotal role in initiating and modulating immune responses by transmitting extracellular signals to intracellular targets. MALT1 Activators are chemical compounds or agents that enhance the activity of MALT1, thereby amplifying the downstream signaling events mediated by the CBM complex.
The activation of MALT1 is a finely tuned process that involves the proteolytic cleavage of its substrates, leading to the activation of various transcription factors and cytokines. MALT1 Activators are believed to promote this proteolytic activity by interacting with MALT1 directly or modulating the activity of other proteins in the CBM complex. By doing so, these compounds can influence immune cell responses, such as cytokine production and cell proliferation, which are crucial for mounting effective immune defenses against pathogens.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a polyphenol found in turmeric, has been observed to modulate various signaling pathways, including NF-κB, which could potentially lead to altered MALT1 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, found in grapes and red wine, can influence sirtuins and NF-κB signaling, potentially impacting MALT1 expression levels. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Found in cruciferous vegetables, sulforaphane is known to modulate NF-κB activity, which may influence MALT1 expression as part of its broader impact on cellular processes. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid with anti-inflammatory properties, capable of modulating various signaling pathways, possibly including those related to MALT1 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Found in green tea, EGCG has been observed to modulate NF-κB signaling, potentially influencing MALT1 expression levels. | ||||||
Ursolic Acid | 77-52-1 | sc-200383 sc-200383A | 50 mg 250 mg | $56.00 $180.00 | 8 | |
Found in apple peels, ursolic acid has anti-inflammatory properties and can modulate various signaling pathways, possibly impacting MALT1 expression. | ||||||
Caffeic acid phenethyl ester | 104594-70-9 | sc-200800 sc-200800A sc-200800B | 20 mg 100 mg 1 g | $71.00 $296.00 $612.00 | 19 | |
CAPE is a component of propolis from bee hives, known to inhibit NF-κB activation, which could influence MALT1 expression levels. | ||||||
Silybin | 22888-70-6 | sc-202812 sc-202812A sc-202812B sc-202812C | 1 g 5 g 10 g 50 g | $55.00 $114.00 $206.00 $714.00 | 6 | |
Silibinin, found in milk thistle, has been shown to modulate NF-κB activity and could potentially impact MALT1 expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a soy-derived isoflavone, modulates various cellular signaling pathways, and could influence MALT1 expression. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Found in pomegranates and berries, ellagic acid has anti-inflammatory properties and can modulate various signaling pathways, potentially affecting MALT1 expression. | ||||||