Ly-6G Activators
Ly-6G activators represent a diverse group of chemicals that modulate Ly-6G expression and activity. Indirect activators exert their influence through various cellular pathways, showcasing the complexity of Ly-6G regulation. Resveratrol indirectly activates Ly-6G by inhibiting NF-κB signaling, emphasizing the regulatory interplay between polyphenols and Ly-6G expression. SB203580 and PD98059 indirectly activate Ly-6G by influencing p38 MAPK and MAPK/ERK pathways, respectively, highlighting the role of MAPK signaling in Ly-6G regulation. LY294002 and Wortmannin indirectly activate Ly-6G through PI3K/Akt signaling modulation, showcasing the interplay between PI3K/Akt signaling and Ly-6G expression. SP600125 indirectly activates Ly-6G by inhibiting JNK signaling, underlining the intricate regulatory network involving JNK and Ly-6G.
Bay 11-7082 indirectly activates Ly-6G by modulating NF-κB signaling, emphasizing the regulatory role of NF-κB in Ly-6G expression. Trichostatin A indirectly activates Ly-6G by epigenetically modulating gene expression, highlighting the role of histone modification in Ly-6G regulation. AZD5363 indirectly activates Ly-6G through Akt/mTOR signaling modulation, showcasing the regulatory interplay between Akt/mTOR signaling and Ly-6G expression. ICG-001 and CHIR-99021 indirectly activate Ly-6G by modulating Wnt/β-catenin signaling, emphasizing the intricate interplay between Wnt signaling and Ly-6G regulation. JSH-23 and CHIR-99021 indirectly activate Ly-6G by modulating NF-κB signaling, highlighting the regulatory role of NF-κB in Ly-6G expression. Collectively, these activators offer valuable insights into the intricate regulatory network governing Ly-6G expression and function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a polyphenol, indirectly activates Ly-6G by inhibiting NF-κB signaling. By suppressing NF-κB, resveratrol promotes Ly-6G expression, which is under the regulatory influence of NF-κB. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580, a p38 MAPK inhibitor, indirectly activates Ly-6G by relieving p38 MAPK-mediated suppression. Inhibition of p38 MAPK by SB203580 attenuates its negative regulation on Ly-6G, leading to increased Ly-6G expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059, a MEK inhibitor, indirectly activates Ly-6G by influencing the MAPK/ERK pathway. Inhibition of MEK by PD98059 disrupts the MAPK/ERK signaling cascade, altering the expression of Ly-6G. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002, a PI3K inhibitor, indirectly activates Ly-6G by disrupting PI3K/Akt signaling. Inhibition of PI3K by LY294002 relieves Akt-mediated suppression, leading to increased Ly-6G expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125, a JNK inhibitor, indirectly activates Ly-6G by inhibiting JNK signaling. Inhibition of JNK by SP600125 relieves its negative regulation on Ly-6G, resulting in increased Ly-6G expression. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
Bay 11-7082, an NF-κB inhibitor, indirectly activates Ly-6G by modulating NF-κB signaling. Inhibition of NF-κB by Bay 11-7082 relieves its suppressive effect on Ly-6G expression, leading to increased Ly-6G levels. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin, a PI3K inhibitor, indirectly activates Ly-6G by influencing PI3K/Akt signaling. Inhibition of PI3K by wortmannin relieves Akt-mediated suppression, leading to increased Ly-6G expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A, a histone deacetylase (HDAC) inhibitor, indirectly activates Ly-6G by epigenetically modulating its gene expression. By inhibiting HDACs, trichostatin A promotes histone acetylation at the Ly-6G promoter region, facilitating transcription. | ||||||
AZD5363 | 1143532-39-1 | sc-503190 | 5 mg | $309.00 | ||
AZD5363, an Akt inhibitor, indirectly activates Ly-6G by modulating the Akt/mTOR signaling pathway. Inhibition of Akt by AZD5363 relieves its negative regulation on Ly-6G expression, leading to increased Ly-6G levels. | ||||||
NFκB Activation Inhibitor II, JSH-23 | 749886-87-1 | sc-222061 sc-222061C sc-222061A sc-222061B | 5 mg 10 mg 50 mg 100 mg | $214.00 $257.00 $1775.00 $2003.00 | 34 | |
JSH-23, an NF-κB inhibitor, indirectly activates Ly-6G by modulating NF-κB signaling. Inhibition of NF-κB by JSH-23 relieves its suppressive effect on Ly-6G expression, leading to increased Ly-6G levels. | ||||||