Date published: 2025-10-12

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LSP1 Inhibitors

LSP1 is involved in the regulation of cell motility and the organization of the cytoskeleton, particularly in hematopoietic cells. The compounds listed above target various aspects of cytoskeletal dynamics and signaling pathways that can affect cell movement and structure. By altering the polymerization and depolymerization of actin, or by modulating the signaling pathways that govern these processes, these compounds could, in theory, affect the function of LSP1 within cells.

The chemical class that might be considered as indirect LSP1 inhibitors would include actin dynamics modulators, kinase inhibitors, and other compounds that target signaling molecules involved in the regulation of the cytoskeleton. They could potentially influence LSP1's function by modifying the actin cytoskeleton, disrupting actin binding, or altering the signaling pathways that regulate these processes. However, the effects of such compounds would likely be broad and influence a wide variety of cellular functions, not just those associated with LSP1.

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