Date published: 2026-4-1

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LRRC3 Activators

LRRC3, or Leucine Rich Repeat Containing 3, is a gene that encodes a protein associated with cellular processes that might be pivotal in maintaining cellular homeostasis. The protein's function, while not completely understood, is thought to be involved in protein-protein interactions, signaling pathways, and possibly in the regulation of other genes' expressions. The expression of LRRC3 can be upregulated by various stimuli, which may trigger intricate signaling cascades within the cell. Understanding the factors that can induce LRRC3 expression is of considerable interest for cellular biology research, as these factors can elucidate the pathways governing cell function and gene expression. Chemicals that induce the expression of LRRC3 do so through diverse mechanisms, each interacting with the cellular machinery in a unique way to promote the transcription of the LRRC3 gene, ultimately leading to increased protein synthesis.

Certain naturally occurring compounds have been studied for their ability to act as potential activators of LRRC3 expression. Resveratrol, a compound found in grapes and berries, is known for its antioxidant properties and could potentially stimulate the transcription of LRRC3 by activating specific pathways that respond to oxidative stress. Similarly, curcumin, the active component of the spice turmeric, could also upregulate LRRC3 expression through its interaction with transcription factors that respond to inflammatory stimuli. On the other hand, compounds like sodium butyrate, a short-chain fatty acid present in dietary fiber, might increase LRRC3 levels by altering the chromatin structure, thereby making the LRRC3 gene more accessible for transcription. It is important to note that while these activators are promising, the precise molecular mechanisms by which they augment LRRC3 expression require further investigation. The study of these chemicals and their interaction with the LRRC3 gene represents an exciting frontier in cellular biology, shedding light on the complex regulatory networks that sustain cellular integrity and function.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin may upregulate LRRC3 expression by activating specific transcription factors associated with anti-inflammatory responses.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol has the potential to stimulate sirtuin pathways that can lead to the enhancement of LRRC3 transcription in cells.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

DL-Sulforaphane could induce the expression of LRRC3 by stimulating the Nrf2 pathway, which plays a role in cellular defense mechanisms.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin might elevate LRRC3 levels by stimulating antioxidant response elements within the promoter region of genes like LRRC3.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate may increase LRRC3 expression by causing hyperacetylation of histones, leading to a more accessible chromatin state for transcriptional activation.

Metformin

657-24-9sc-507370
10 mg
$79.00
2
(0)

Metformin is known to activate AMPK, which could stimulate a pathway leading to the enhanced expression of LRRC3 as part of metabolic regulation.

3,3′-Diindolylmethane

1968-05-4sc-204624
sc-204624A
sc-204624B
sc-204624C
sc-204624D
sc-204624E
100 mg
500 mg
5 g
10 g
50 g
1 g
$37.00
$65.00
$89.00
$421.00
$681.00
$66.00
8
(1)

This compound might stimulate LRRC3 expression via the interaction with estrogen receptor pathways, which can alter the transcription of various genes including LRRC3.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid could induce the upregulation of LRRC3 by binding to its nuclear receptors and promoting transcriptional activation of retinoic acid-responsive genes.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

This polyphenol may stimulate the expression of LRRC3 by activating cellular pathways linked to antioxidant responses and epigenetic modifications.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein has the capacity to stimulate transcriptional processes that may upregulate the expression of LRRC3, acting via phytoestrogenic pathways.