Low-density lipoprotein receptor-related protein 3 (LRP3) is a protein that in humans is encoded by the LRP3 gene. LRP3 belongs to the low-density lipoprotein receptor (LDLR) family, a group of proteins that play crucial roles in lipid metabolism, nutrient uptake, and cellular signaling pathways.LDLR family members are characterized by their ability to bind and internalize specific types of lipoproteins from the bloodstream, facilitating their transport into cells where they can be metabolized. This function is crucial for maintaining lipid homeostasis within the body.
In addition to roles in lipid metabolism, LRP3 and other LDLR family members may also function as signaling receptors, interacting with other proteins to regulate cellular processes such as proliferation, migration, and differentiation.Dysfunction of LDLR family proteins is associated with various diseases, including familial hypercholesterolemia and atherosclerosis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $31.00 $89.00 $135.00 $443.00 | 13 | |
Statins, known for lowering cholesterol, can influence LDL receptor family activity and may indirectly affect LRP3. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid affects gene expression and could potentially modulate LRP3 expression or activity. | ||||||
(S)-Pramipexole Dihydrochloride | 104632-25-9 | sc-212895 | 10 mg | $164.00 | ||
RAP interacts with LDL receptor family members and could affect LRP3-mediated endocytosis. | ||||||
Cephapirin Benzathine | 97468-37-6 | sc-504765 | 10 mg | $193.00 | ||
As the natural ligand for LDL receptors, LDL might influence LRP3-mediated endocytosis. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
LPS, as an activator of immune responses, might influence LRP3 in the context of inflammation. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D influences gene expression and cellular signaling, potentially impacting LRP3 activity. | ||||||