LOXL4 Activators

LOXL4 Activators, as defined in this context, are a class of compounds that can indirectly influence the activity of LOXL4. These activators function primarily by providing essential cofactors, modulating gene expression, or altering cellular environments that are conducive to LOXL4's enzymatic activity. Cofactors like Copper Sulfate and Manganese Chloride are critical for LOXL4's catalytic function, and their presence can enhance the enzyme's activity. Antioxidants such as Ascorbic Acid, Hydrogen Peroxide, N-Acetylcysteine, and Taurine can indirectly influence LOXL4 by maintaining an optimal oxidative environment necessary for its activity. In contrast, compounds like β-Aminopropionitrile and D-Penicillamine, known for their interactions with lysyl oxidases, might modulate LOXL4 activity indirectly under specific conditions.

Furthermore, compounds influencing gene expression and cellular signaling, such as Retinoic Acid, EGCG, Curcumin, and Resveratrol, can potentially affect LOXL4 indirectly. These compounds may influence the expression levels of LOXL4 or the availability of its substrates by modulating related pathways.