LOC728720 Inhibitors
LOC728720 can contains Kinase inhibitors like Staurosporine, U0126, and PD98059 are capable of altering cell signaling, which can modify the activity of numerous proteins, potentially including LOC728720. Compounds such as Cycloheximide and Actinomycin D affect protein synthesis and mRNA synthesis, respectively, and can therefore influence the levels of LOC728720 protein if it is actively synthesized and regulated at the transcriptional level. The mTOR pathway, a critical regulator of cell growth, can be targeted by Rapamycin, which may also impact LOC728720-related processes.
Inhibitors such as LY294002 affect PI3K signaling and can consequently modulate several cellular functions that might intersect with LOC728720's role. Bortezomib and Chloroquine interfere with protein degradation pathways, such as the proteasome and autophagy-lysosome pathways, potentially affecting the stability and recycling of LOC728720. Compounds like Brefeldin A and Thapsigargin disrupt protein transport and calcium homeostasis, respectively, which can have wide-ranging effects on cellular processes and may indirectly affect LOC728720. Lastly, Wnt-C59 acts on the Wnt/β-catenin signaling pathway, which is essential for cell differentiation and proliferation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can disrupt cell signaling pathways, potentially affecting the function or expression of LOC728720. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis by interfering with the translocation step in protein synthesis, potentially reducing the overall levels of LOC728720. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Binds to DNA and inhibits RNA polymerase, potentially decreasing LOC728720 mRNA synthesis if it is transcriptionally regulated. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can affect cell growth and proliferation, potentially influencing the biological processes where LOC728720 is involved. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can alter cell survival and proliferation signaling pathways, potentially modulating LOC728720's role. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that can increase cellular protein levels by preventing their degradation, potentially affecting the stability of LOC728720. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts protein transport by inhibiting the exchange of protein and other molecules across the Golgi apparatus, potentially affecting LOC728720. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
A SERCA pump inhibitor that leads to an increase in cytosolic calcium levels, potentially affecting calcium-dependent processes involving LOC728720. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An MEK inhibitor that can disrupt MAPK/ERK signaling, which may influence LOC728720 activity if it is linked to this pathway. | ||||||
Wnt-C59 | 1243243-89-1 | sc-475634 sc-475634A sc-475634B | 5 mg 10 mg 50 mg | $210.00 $320.00 $1250.00 | 1 | |
An inhibitor of Wnt/β-catenin signaling, which might impact LOC728720 if it plays a role in this pathway. | ||||||