LOC645282 Inhibitors
Kinase inhibitors like Imatinib and Ibrutinib have the capacity to modulate signaling cascades by inhibiting specific tyrosine kinases, which could impact the activity of LOC645282 if it is phosphorylated by these kinases or involved in the same signaling pathway. Bortezomib, by inhibiting the proteasome, can influence the degradation of a broad range of proteins, potentially including LOC645282 if it is marked for degradation by this cellular machinery.
Compounds such as Thapsigargin and Cyclosporine A affect intracellular calcium levels and calcineurin activity, respectively, which could alter the function of LOC645282 if its activity is calcium-dependent or if it interacts with components of the immune response. Z-VAD-FMK, a caspase inhibitor, could modulate the activity of LOC645282 by affecting apoptotic processes, while PD98059 and U0126, both MEK inhibitors, and SB431542, a TGF-β receptor inhibitor, could influence LOC645282 through their effects on MAPK/ERK signaling and TGF-β-mediated cellular processes.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Targets tyrosine kinases and can inhibit related signaling which may affect LOC645282's activity if kinase-dependent. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $70.00 $282.00 | 6 | |
Interferes with microtubule dynamics and can disrupt cell division, potentially affecting LOC645282 if involved in this process. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Disrupts calcium homeostasis by inhibiting the SERCA pump, possibly affecting LOC645282 if calcium-signaling dependent. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $153.00 | 5 | |
Inhibits Bruton’s tyrosine kinase and can influence B-cell receptor signaling, affecting LOC645282 if part of this pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR signaling which can affect cell growth and proliferation, potentially affecting LOC645282 activity. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Inhibits the proteasome, potentially affecting the degradation of LOC645282 if it is a substrate. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Inhibits calcineurin and can alter NFAT pathway signaling, which may affect LOC645282 if involved in immune response regulation. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $74.00 | 256 | |
Inhibits caspases and can prevent apoptosis, potentially affecting LOC645282 if it plays a role in cell death pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK and can affect MAPK/ERK signaling, potentially altering LOC645282's activity if connected to this pathway. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Targets MEK1/2 specifically and can disrupt signaling pathways, potentially affecting LOC645282 activity. | ||||||