LOC644070 Inhibitors
LOC644070 inhibitors staurosporine and chelerythrine target kinases, which are central to many signaling pathways, possibly affecting LOC644070 if it is phosphorylated by these enzymes. U0126 and PD98059 are specific to the MEK enzymes within the MAPK/ERK pathway and could influence LOC644070 if it is part of this cascade. Rapamycin and LY294002 target the mTOR and PI3K/AKT pathways, respectively, which are crucial in regulating cell growth, survival, and metabolism, possibly impacting LOC644070 if it is associated with these pathways.
SB203580 and SP600125 inhibit p38 MAPK and JNK, affecting inflammatory and stress response pathways, as well as apoptosis and differentiation, which might alter LOC644070 activity if it is linked to these processes. Thapsigargin and 2-Deoxy-D-glucose disrupt calcium signaling and glycolysis, respectively, potentially affecting LOC644070 if it is regulated by calcium or involved in energy metabolism. Z-VAD-FMK inhibits caspases to affect apoptotic signaling, which could alter LOC644070 function if it plays a role in apoptosis. Lastly, AG490 inhibits JAK2 potentially affecting cytokine signaling and, by extension, LOC644070 if it is involved in this signaling pathway.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A potent kinase inhibitor that can affect multiple signaling pathways by inhibiting phosphorylation events, which might alter the function of LOC644070 if it is regulated by phosphorylation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, which can impact protein synthesis and cell growth pathways, potentially altering the function of LOC644070 if it is connected to these processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor that can disrupt the PI3K/AKT pathway, potentially influencing LOC644070 if it plays a role in cell survival or metabolism regulated by this pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
P38 MAPK inhibitor that might affect inflammatory response and stress response pathways, potentially altering LOC644070 activity if it is part of these responses. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
SERCA pump inhibitor that can elevate cytosolic calcium levels, potentially affecting LOC644070 if it is regulated by calcium signaling. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
Glycolysis inhibitor that can disrupt energy metabolism, possibly influencing LOC644070 if it is involved in metabolic pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor that can block the MAPK/ERK pathway, potentially affecting LOC644070 if it is regulated by this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that might affect apoptosis and cell differentiation, potentially influencing LOC644070 if it is involved in these processes. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $75.00 | 256 | |
A broad-spectrum caspase inhibitor that can affect apoptosis, potentially altering the function of LOC644070 if it plays a role in apoptotic signaling. | ||||||
Chelerythrine chloride | 3895-92-9 | sc-3547 sc-3547A | 5 mg 25 mg | $90.00 $317.00 | 17 | |
PKC inhibitor that can affect multiple signaling pathways mediated by protein kinase C, potentially influencing LOC644070 if it is regulated by PKC. | ||||||