Tyrosine kinase inhibitors like Imatinib, Erlotinib, and Lapatinib offer a mechanism to interrupt signaling pathways that govern cell cycle progression, survival, and proliferation. The blockade of these pathways by such inhibitors can alter the function and regulation of proteins, including LOC641696, that are presumed to be associated with these signaling networks. In a similar vein, compounds targeting receptor tyrosine kinases, such as Sunitinib, Pazopanib, and Vandetanib, can disrupt the cascade of signals that might modulate the activity of LOC641696, particularly if this protein plays a role in pathways like angiogenesis or cell growth.
Inhibitors that act on the MAPK/ERK pathway, including Sorafenib and Selumetinib, can suppress the MAPK/ERK signaling, potentially leading to a decrease in the activity of proteins that function as part of this pathway. By impeding these kinases, the activity of LOC641696 can be influenced, provided that it is a downstream effector of this signaling cascade. Additionally, mTOR inhibitors like Temsirolimus can lead to a reduction in protein synthesis and can impact cellular growth and metabolism, potentially affecting the synthesis and function of LOC641696.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
BCR-ABL tyrosine kinase inhibitor that can suppress the activity of kinases involved in the signaling cascades that may regulate LOC641696. | ||||||
Erlotinib, Free Base | 183321-74-6 | sc-396113 sc-396113A sc-396113B sc-396113C sc-396113D | 500 mg 1 g 5 g 10 g 100 g | $85.00 $132.00 $287.00 $495.00 $3752.00 | 42 | |
EGFR inhibitor that can block the epidermal growth factor receptor signaling, which can downregulate proteins like LOC641696 if they are part of this pathway. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Raf kinase inhibitor that can inhibit the MAPK/ERK pathway, potentially decreasing the activity of proteins like LOC641696 if they are downstream effectors. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $150.00 $920.00 | 5 | |
Receptor tyrosine kinase inhibitor that can block signaling pathways involved in cell proliferation, which can affect LOC641696 if it is associated with these pathways. | ||||||
Vandetanib | 443913-73-3 | sc-220364 sc-220364A | 5 mg 50 mg | $167.00 $1353.00 | ||
VEGFR inhibitor that can disrupt angiogenesis signaling, potentially affecting proteins like LOC641696 that may be regulated by this pathway. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Angiogenesis inhibitor that can modulate the immune response and inhibit growth factor signaling, potentially influencing the activity of LOC641696. | ||||||
Lapatinib | 231277-92-2 | sc-353658 | 100 mg | $412.00 | 32 | |
Dual tyrosine kinase inhibitor that can target EGFR and HER2/neu, which can affect proteins like LOC641696 if they are involved in these pathways. | ||||||
Pazopanib | 444731-52-6 | sc-396318 sc-396318A | 25 mg 50 mg | $127.00 $178.00 | 2 | |
Multi-tyrosine kinase inhibitor that can affect various signaling pathways, potentially altering the activity of proteins like LOC641696. | ||||||
Selumetinib | 606143-52-6 | sc-364613 sc-364613A sc-364613B sc-364613C sc-364613D | 5 mg 10 mg 100 mg 500 mg 1 g | $28.00 $80.00 $412.00 $1860.00 $2962.00 | 5 | |
MEK inhibitor that can impact the MAPK/ERK pathway, which can decrease the activity of proteins like LOC641696 if they are part of this cascade. | ||||||