The chemical class known as LOC100041115 Inhibitors represents a specific set of compounds developed to target and inhibit the activity of the gene product of LOC100041115. This gene, identified through extensive genetic and molecular research, is involved in various cellular processes and functions. The role of LOC100041115 is highly context-dependent, which means its function can significantly vary depending on the specific cellular environment and external stimuli. Inhibitors targeting LOC100041115 are meticulously crafted to selectively bind to the proteins or enzymes produced as a result of this gene's expression. This targeted binding mechanism is fundamental to the inhibitors' functionality, as it directly affects the biochemical pathways in which the LOC100041115 gene product is involved. By modulating the activity of this gene product, the inhibitors aim to alter the associated cellular processes, potentially impacting specific cellular functions and mechanisms.
The development of LOC100041115 Inhibitors is a complex and interdisciplinary task, involving the integration of molecular biology, chemistry, and pharmacology. The process begins with a comprehensive understanding of the structure and function of the LOC100041115 gene product. Advanced techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are utilized to gain a detailed understanding of the target molecule. This foundational knowledge is crucial for the rational design of inhibitors that are both effective in their interaction with the target and exhibit a high degree of specificity. Typically, these inhibitors are small molecules, designed for efficient penetration into cellular membranes and to establish a stable and potent interaction with their target. The molecular design of these inhibitors is carefully optimized to ensure robust interactions with the target molecule, often involving hydrogen bonds, hydrophobic interactions, and van der Waals forces. The efficacy of these inhibitors is evaluated through various biochemical assays in vitro. These assays are essential for determining the inhibitors' potency, specificity, and overall behavior under controlled experimental conditions. This research is vital for understanding the inhibitors' mechanism of action and for further exploration into their potential impact on the complex network of cellular pathways influenced by LOC100041115.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Inhibits eukaryotic RNA polymerase II, causing a general reduction in mRNA synthesis and gene expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Interferes with RNA polymerase by binding to DNA, inhibiting RNA synthesis and affecting gene expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II transcriptional elongation, leading to a decrease in gene expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Inhibits the activity of RNA polymerase II, leading to a general suppression of transcription and gene expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can cause DNA demethylation, potentially affecting gene expression. | ||||||
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $107.00 $416.00 $1248.00 | 35 | |
Inhibits the export of mRNA from the nucleus to the cytoplasm, reducing gene expression at a post-transcriptional level. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $166.00 $322.00 | 436 | |
Causes premature chain termination during translation, resulting in the inhibition of protein synthesis. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Inhibits eukaryotic peptide chain elongation by affecting the ribosome, leading to a reduction in protein synthesis. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Blocks the translocation step in protein synthesis on ribosomes, leading to inhibition of protein synthesis and gene expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits the first step in glycoprotein biosynthesis, which can indirectly affect protein synthesis and gene expression. | ||||||