LOC100039560 inhibitors are a class of chemical compounds developed to target and inhibit the activity of the protein encoded by the gene LOC100039560. This gene is among those identified in genomic studies, notable for its unique expression profile, suggesting its involvement in specific cellular functions. While the full biological role of the protein encoded by LOC100039560 is not completely understood, it is believed to participate in distinct cellular pathways, as indicated by initial genomic and proteomic analyses. The development of inhibitors targeting this protein involves a thorough understanding of its molecular structure and how it functions within cellular systems. The primary aim of designing LOC100039560 inhibitors is to disrupt the functional activities of this protein, thus gaining insights into its role in cellular processes and potentially influencing these processes. This goal requires identifying critical sites or domains on the protein that are essential for its functionality and creating molecules that can effectively bind to and inhibit these sites.
The process of developing LOC100039560 inhibitors is complex and involves a multidisciplinary approach, incorporating biochemistry, molecular biology, and pharmacology. Researchers working on this initiative focus on determining the structural details of the LOC100039560 protein, using various advanced techniques to map its structure, particularly its functional domains. This structural understanding is crucial for the targeted design of inhibitors that are both specific to their target and effective in their action. The interaction between these inhibitors and the LOC100039560 protein is key to their efficacy. The inhibitors must bind to the protein in a manner that disrupts its ability to interact with other cellular components or perform its normal functions. Typically, this results in the formation of a complex between the inhibitor and specific regions on the protein, necessitating a highly accurate match in molecular structures. In addition to their binding properties, the design of LOC100039560 inhibitors also considers factors such as the compound's stability, solubility, and its ability to reach and interact effectively with the target site within biological systems. Researchers strive to optimize the pharmacokinetic properties of these inhibitors, ensuring they possess appropriate hydrophobic and hydrophilic characteristics and an optimal molecular size and shape for efficient interaction. The development of LOC100039560 inhibitors highlights the advanced level of current research in molecular targeting and underscores the complexities involved in designing inhibitors for proteins that are relatively uncharacterized but may play significant roles in biological processes.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Binds to DNA and inhibits RNA polymerase, thus blocking RNA synthesis. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Inhibits RNA polymerase II, which is responsible for mRNA synthesis. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Binds to bacterial RNA polymerase, inhibiting transcription initiation. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Analog of adenosine that can terminate mRNA chain elongation. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits RNA polymerase II transcription elongation. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Inhibits transcription by affecting the activity of RNA polymerase II. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Inhibits cyclin-dependent kinases and can indirectly reduce transcription. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inhibits DNA topoisomerase I, causing DNA damage and affecting transcription. | ||||||
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $105.00 $408.00 $1224.00 | 35 | |
Inhibits exportin 1 (CRM1), preventing nuclear export of certain proteins and RNA. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Inhibits initiation of translation and could downregulate protein synthesis. |