Date published: 2025-10-15

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LO CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. LO gene silencers are available as LO CRISPR/Cas9 Knockout plasmids and LO Double Nickase Plasmids. LO CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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LO CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

5-LO CRISPR/Cas9 KO Plasmid (h)

sc-401239hGene KnockoutGFP0
(0)

5-LO CRISPR/Cas9 KO Plasmid (h2)

sc-401239-KO-2hGene KnockoutGFP0
(0)

5-LO HDR Plasmid (h2)

sc-401239-HDR-2hHomology Directed RepairPuromycin0
(0)

5-LO Double Nickase Plasmid (h)

sc-401239-NIChGene KnockoutPuromycin0
(0)

5-LO Double Nickase Plasmid (h2)

sc-401239-NIC-2hGene KnockoutPuromycin0
(0)

5-LO CRISPR/Cas9 KO Plasmid (m)

sc-419091mGene KnockoutGFP0
(0)

5-LO Double Nickase Plasmid (m)

sc-419091-NICmGene KnockoutPuromycin0
(0)

5-LO Double Nickase Plasmid (m2)

sc-419091-NIC-2mGene KnockoutPuromycin0
(0)

12-LO CRISPR/Cas9 KO Plasmid (h)

sc-403010hGene KnockoutGFP
1
(0)

12-LO HDR Plasmid (h)

sc-403010-HDRhHomology Directed RepairPuromycin
1
(0)

12-LO Double Nickase Plasmid (h)

sc-403010-NIChGene KnockoutPuromycin
1
(0)

12-LO Double Nickase Plasmid (h2)

sc-403010-NIC-2hGene KnockoutPuromycin
1
(0)

12-LO CRISPR/Cas9 KO Plasmid (m)

sc-419086mGene KnockoutGFP0
(0)

12-LO HDR Plasmid (m)

sc-419086-HDRmHomology Directed RepairPuromycin0
(0)

12-LO Double Nickase Plasmid (m)

sc-419086-NICmGene KnockoutPuromycin0
(0)

12-LO Double Nickase Plasmid (m2)

sc-419086-NIC-2mGene KnockoutPuromycin0
(0)

15-LO CRISPR/Cas9 KO Plasmid (h2)

sc-401591-KO-2hGene KnockoutGFP
1
(0)

15-LO HDR Plasmid (h2)

sc-401591-HDR-2hHomology Directed RepairPuromycin
1
(0)

15-LO Double Nickase Plasmid (h)

sc-401591-NIChGene KnockoutPuromycin
1
(0)

15-LO Double Nickase Plasmid (h2)

sc-401591-NIC-2hGene KnockoutPuromycin
1
(0)

15-LO2 CRISPR/Cas9 KO Plasmid (h)

sc-404699hGene KnockoutGFP0
(0)

15-LO2 HDR Plasmid (h)

sc-404699-HDRhHomology Directed RepairPuromycin0
(0)

15-LO2 Double Nickase Plasmid (h)

sc-404699-NIChGene KnockoutPuromycin0
(0)

15-LO2 Double Nickase Plasmid (h2)

sc-404699-NIC-2hGene KnockoutPuromycin0
(0)

15-LO2 CRISPR/Cas9 KO Plasmid (m)

sc-419090mGene KnockoutGFP0
(0)

15-LO2 Double Nickase Plasmid (m)

sc-419090-NICmGene KnockoutPuromycin0
(0)

15-LO2 Double Nickase Plasmid (m2)

sc-419090-NIC-2mGene KnockoutPuromycin0
(0)

LO CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

5-LO CRISPR Activation Plasmid (h)

sc-401239-ACThGene ActivationPuro, Blast, Hygro0
(0)

5-LO CRISPR Activation Plasmid (h2)

sc-401239-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

5-LO Lentiviral Activation Particles (h)

sc-401239-LAChGene ActivationPuro, Blast, Hygro0
(0)

5-LO Lentiviral Activation Particles (h2)

sc-401239-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

5-LO CRISPR Activation Plasmid (m)

sc-419091-ACTmGene ActivationPuro, Blast, Hygro0
(0)

5-LO CRISPR Activation Plasmid (m2)

sc-419091-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

5-LO Lentiviral Activation Particles (m)

sc-419091-LACmGene ActivationPuro, Blast, Hygro0
(0)

5-LO Lentiviral Activation Particles (m2)

sc-419091-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

12-LO CRISPR Activation Plasmid (h)

sc-403010-ACThGene ActivationPuro, Blast, Hygro
1
(0)

12-LO CRISPR Activation Plasmid (h2)

sc-403010-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

12-LO Lentiviral Activation Particles (h)

sc-403010-LAChGene ActivationPuro, Blast, Hygro
1
(0)

12-LO Lentiviral Activation Particles (h2)

sc-403010-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

12-LO CRISPR Activation Plasmid (m)

sc-419086-ACTmGene ActivationPuro, Blast, Hygro0
(0)

12-LO CRISPR Activation Plasmid (m2)

sc-419086-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

12-LO Lentiviral Activation Particles (m)

sc-419086-LACmGene ActivationPuro, Blast, Hygro0
(0)

12-LO Lentiviral Activation Particles (m2)

sc-419086-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

15-LO CRISPR Activation Plasmid (h)

sc-401591-ACThGene ActivationPuro, Blast, Hygro
1
(0)

15-LO CRISPR Activation Plasmid (h2)

sc-401591-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

15-LO Lentiviral Activation Particles (h)

sc-401591-LAChGene ActivationPuro, Blast, Hygro
1
(0)

15-LO Lentiviral Activation Particles (h2)

sc-401591-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

15-LO2 CRISPR Activation Plasmid (h)

sc-404699-ACThGene ActivationPuro, Blast, Hygro0
(0)

15-LO2 CRISPR Activation Plasmid (h2)

sc-404699-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

15-LO2 Lentiviral Activation Particles (h)

sc-404699-LAChGene ActivationPuro, Blast, Hygro0
(0)

15-LO2 Lentiviral Activation Particles (h2)

sc-404699-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

15-LO2 CRISPR Activation Plasmid (m)

sc-419090-ACTmGene ActivationPuro, Blast, Hygro0
(0)

15-LO2 CRISPR Activation Plasmid (m2)

sc-419090-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

15-LO2 Lentiviral Activation Particles (m)

sc-419090-LACmGene ActivationPuro, Blast, Hygro0
(0)

15-LO2 Lentiviral Activation Particles (m2)

sc-419090-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)