Date published: 2025-10-18

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Lipoic Acid Activators

Lipoic Acid Activators refer to a class of chemical compounds that are known for their ability to enhance or potentiate the functions of lipoic acid, also known as alpha-lipoic acid or thioctic acid. Lipoic acid is a naturally occurring molecule in the body and is an essential co-factor for various enzymatic reactions involved in energy metabolism, particularly within the mitochondria. It plays a critical role in the conversion of carbohydrates, fats, and proteins into cellular energy through its participation in enzymatic complexes like pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase. Lipoic acid is also recognized for its potent antioxidant properties, protecting cells and tissues from oxidative stress and free radical damage.

Lipoic acid activators, while not directly interacting with lipoic acid itself, often function by supporting or augmenting the processes in which lipoic acid is involved. These activators can include essential co-factors like biotin, which assists lipoic acid-dependent enzymes, or other antioxidants such as vitamins C and E, which may work synergistically with lipoic acid to combat oxidative stress. Essential minerals like magnesium, zinc, and selenium are also integral in the activation and function of lipoic acid-dependent enzymes. Furthermore, compounds like acetyl-L-carnitine may complement lipoic acid in promoting mitochondrial health and energy production. The interplay between lipoic acid and its activators highlights the intricate balance required for optimal cellular metabolism and protection against oxidative damage.

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D-(+)-Biotin

58-85-5sc-204706
sc-204706A
sc-204706B
1 g
5 g
25 g
$40.00
$105.00
$326.00
1
(4)

Biotin is a coenzyme that can indirectly support lipoic acid by acting as a cofactor for lipoic acid-dependent enzymes, such as pyruvate dehydrogenase.

Coenzyme Q10

303-98-0sc-205262
sc-205262A
1 g
5 g
$70.00
$180.00
1
(1)

CoQ10 is an antioxidant that may complement lipoic acid's antioxidant activity and help protect cells from oxidative damage.

L-Ascorbic acid, free acid

50-81-7sc-202686
100 g
$45.00
5
(1)

Vitamin C can regenerate lipoic acid, extending its antioxidant capacity within the body.

(+)-α-Tocopherol

59-02-9sc-214454
sc-214454A
sc-214454B
10 g
25 g
100 g
$42.00
$61.00
$138.00
(1)

Vitamin E can work synergistically with lipoic acid to combat oxidative stress and protect cells from free radical damage.

Magnesium chloride

7786-30-3sc-255260C
sc-255260B
sc-255260
sc-255260A
10 g
25 g
100 g
500 g
$27.00
$34.00
$47.00
$123.00
2
(1)

Magnesium is essential for the proper function of lipoic acid-dependent enzymes, such as pyruvate dehydrogenase.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc is involved in the activation of lipoic acid-dependent enzymes and can indirectly support their activity.

Selenium

7782-49-2sc-250973
50 g
$61.00
1
(1)

Selenium is another trace element that may enhance lipoic acid's antioxidant properties and cellular functions.

Acetyl-L-carnitine chloride

5080-50-2sc-210747
1 g
$52.00
(1)

Acetyl-L-carnitine is a compound that may work synergistically with lipoic acid to support mitochondrial function and energy production.

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$33.00
$73.00
$265.00
$112.00
34
(1)

NAC is a precursor to glutathione, an antioxidant that can complement lipoic acid's antioxidant activity.

Silymarin group, mixture of isomers

65666-07-1sc-301806
50 g
$319.00
(0)

Silymarin may enhance the antioxidant effects of lipoic acid and support liver health.