Lipocalin-14 Activators
Obp2b, an odorant binding protein, plays a vital role in the olfactory system of Mus musculus by facilitating the transport of odorant molecules. Its activation is crucial for efficient odor perception, and it can be directly or indirectly activated by various volatile compounds found in the environment. Obp2b is primarily localized in the extracellular space, where it functions as an odorant carrier. Its activation is linked to the binding of specific odorant molecules, such as cis-3-hexen-1-ol, isoamyl acetate, beta-ionone, and 2-heptanone, to its odorant binding site. These interactions induce conformational changes in Obp2b, enhancing its role in odorant transport and promoting efficient odor perception by facilitating the binding of specific odor molecules to olfactory receptors.
In addition to direct activation by odorants, Obp2b can be indirectly activated by volatile compounds like limonene, alpha-pinene, eugenol, citronellal, hexanal, linalool, geraniol, and methyl salicylate. These compounds modulate olfactory receptor signaling pathways and receptor sensitivity, potentially supporting Obp2b's function in odorant transport and contributing to accurate odor perception. In conclusion, Obp2b's activation is a critical step in the olfaction process of house mice. It enables the efficient detection of specific odors by promoting the transport of odorant molecules to olfactory receptors. Understanding the mechanisms of Obp2b activation is essential for unraveling the complexities of olfaction in mice and sheds light on the intricate interplay between odorant binding proteins and the perception of environmental odors. Further research is needed to explore the precise details of Obp2b's activation and its role in odor recognition.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
D-Limonene can indirectly activate Obp2b by modulating olfactory receptor signaling pathways. It influences the activation of olfactory receptors, potentially supporting Obp2b's function in the transport of odorants and contributing to efficient odor perception. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene indirectly activates Obp2b by enhancing olfactory receptor sensitivity. It influences the responsiveness of olfactory receptors to odorants, potentially promoting Obp2b's role in odorant transport and aiding in effective odor perception. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol indirectly activates Obp2b by influencing olfactory receptor sensitivity and signaling cascades. It modulates the activity of olfactory receptors, potentially supporting Obp2b's function in odorant binding and transport, enhancing the overall olfactory perception process. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate can directly activate Obp2b through binding interactions at the odorant binding site. This binding triggers a conformational change in Obp2b, promoting its role in odorant transport and enhancing its function in the efficient detection of specific odor molecules. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal indirectly activates Obp2b by modulating olfactory receptor signaling pathways. It affects the responsiveness of olfactory receptors to odorants, potentially supporting Obp2b's function in odorant transport and contributing to the accurate perception of odors. | ||||||
beta-Ionone | 14901-07-6 | sc-291976 | 25 ml | $83.00 | ||
Beta-ionone can directly activate Obp2b by binding to its odorant binding site. This interaction induces a conformational change in Obp2b, enhancing its role in odorant transport and promoting efficient odor perception by facilitating the binding of specific odor molecules. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal indirectly activates Obp2b by influencing olfactory receptor signaling pathways. It modulates the responsiveness of olfactory receptors to odorants, potentially supporting Obp2b's function in odorant binding and transport, enhancing the overall olfactory perception process. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool indirectly activates Obp2b by modulating olfactory receptor sensitivity and signaling cascades. It affects the activity of olfactory receptors, potentially supporting Obp2b's function in odorant transport and contributing to the accurate perception of various odors. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone can directly activate Obp2b through binding interactions at the odorant binding site. This binding triggers a conformational change in Obp2b, promoting its role in odorant transport and enhancing its function in the efficient detection of specific odor molecules. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol indirectly activates Obp2b by modulating olfactory receptor signaling pathways. It influences the responsiveness of olfactory receptors to odorants, potentially supporting Obp2b's function in odorant binding and transport, enhancing the overall olfactory perception process. | ||||||