Limd1 inhibitors belong to a distinctive chemical class characterized by their ability to modulate the Limd1 protein, a critical regulator of cellular processes. Limd1, short for LIM domain-containing protein 1, is a multifunctional protein that plays a pivotal role in various cellular functions, including cell growth, differentiation, and migration. The Limd1 protein is characterized by the presence of LIM domains, which are zinc finger-like structures that mediate protein-protein interactions. These interactions, in turn, influence downstream signaling pathways and cellular responses.
Limd1 inhibitors are designed to selectively bind to the Limd1 protein, thereby interfering with its normal function. The structural components of these inhibitors are meticulously crafted to complement the binding site on Limd1, disrupting the protein's interactions with other cellular components. By modulating Limd1 activity, these inhibitors have the potential to influence diverse cellular processes, offering researchers a valuable tool for investigating the underlying mechanisms of cellular regulation. The development of Limd1 inhibitors represents a targeted approach to manipulating cellular pathways, allowing scientists to explore the intricacies of Limd1-mediated signaling and its impact on cellular homeostasis. As researchers continue to unravel the complexities of Limd1 function, the chemical class of Limd1 inhibitors remains an integral asset in advancing our understanding of fundamental cellular
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor, which may indirectly affect LIMD1 activities by altering actin cytoskeleton dynamics and cell morphology. | ||||||
Verteporfin | 129497-78-5 | sc-475698 sc-475698A | 10 mg 100 mg | $354.00 $2764.00 | 5 | |
A compound known to inhibit YAP-TEAD interactions in the Hippo pathway, which can influence LIMD1-mediated cellular functions. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
A Src family kinase inhibitor, potentially affecting signaling cascades that intersect with LIMD1's role in the cellular matrix and adhesion. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, potentially affecting cell growth and proliferation pathways linked with LIMD1's function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor that can modify signaling pathways involving LIMD1. | ||||||
Gö 6976 | 136194-77-9 | sc-221684 | 500 µg | $227.00 | 8 | |
A PKC inhibitor, which may alter cell adhesion and migration processes that involve LIMD1. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $31.00 $89.00 $135.00 $443.00 | 13 | |
An HMG-CoA reductase inhibitor, which may have an impact on cellular functions regulated by LIMD1 through cholesterol biosynthesis pathways. | ||||||