Date published: 2026-4-4

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LGR5 Antibodies

Santa Cruz Biotechnology provides a broad selection of LGR5 monoclonal antibodies for research focused on understanding LGR5 protein functions. The monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). LGR5, or Leucine-rich repeat-containing G protein-coupled receptor 5, serves as a critical marker for stem cells in various tissues, particularly in the intestinal epithelium. LGR5 plays a significant role in regulating stem cell proliferation and differentiation, making it essential for maintaining tissue homeostasis and regeneration. Research has shown that LGR5 expression is altered in several cancers, highlighting its importance in both developmental biology and oncology research. Understanding LGR5's role in stem cell biology has opened new avenues for investigating tissue regeneration and cancer development. Ongoing studies continue to reveal new functions and regulatory mechanisms of LGR5 in different biological processes. LGR5 research has significant implications for developing targeted therapies in regenerative medicine and cancer treatment. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of LGR5's role in health and disease.

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LGR5 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

LGR5 Antibody (634J2E)

sc-517661mouse IgG1689-719 (h)WB, FCMh
1
(0)

LGR5 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LGR5 CRISPR/Cas9 KO Plasmid (h)

sc-400726hGene KnockoutGFP0
(0)

LGR5 HDR Plasmid (h)

sc-400726-HDRhHomology Directed RepairPuromycin0
(0)

LGR5 Double Nickase Plasmid (h)

sc-400726-NIChGene KnockoutPuromycin0
(0)

LGR5 Double Nickase Plasmid (h2)

sc-400726-NIC-2hGene KnockoutPuromycin0
(0)

LGR5 CRISPR/Cas9 KO Plasmid (m)

sc-420320mGene KnockoutGFP0
(0)

LGR5 HDR Plasmid (m)

sc-420320-HDRmHomology Directed RepairPuromycin0
(0)

LGR5 Double Nickase Plasmid (m)

sc-420320-NICmGene KnockoutPuromycin0
(0)

LGR5 Double Nickase Plasmid (m2)

sc-420320-NIC-2mGene KnockoutPuromycin0
(0)

LGR5 CRISPR Activation Products

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LGR5 CRISPR Activation Plasmid (h)

sc-400726-ACThGene ActivationPuro, Blast, Hygro0
(0)

LGR5 CRISPR Activation Plasmid (h2)

sc-400726-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LGR5 CRISPR Activation Plasmid (m)

sc-420320-ACTmGene ActivationPuro, Blast, Hygro0
(0)

LGR5 CRISPR Activation Plasmid (m2)

sc-420320-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

LGR5 Lentiviral Activation Particles (m)

sc-420320-LACmGene ActivationPuro, Blast, Hygro0
(0)

LGR5 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LGR5 siRNA (h)

sc-62559hGene SilencingN/A
2
(0)

LGR5 shRNA Plasmid (h)

sc-62559-SHhGene SilencingPuromycin
2
(0)

LGR5 shRNA (h) Lentiviral Particles

sc-62559-VhGene SilencingPuromycin
2
(0)

LGR5 siRNA (m)

sc-62560mGene SilencingN/A0
(0)

LGR5 shRNA Plasmid (m)

sc-62560-SHmGene SilencingPuromycin0
(0)

LGR5 shRNA (m) Lentiviral Particles

sc-62560-VmGene SilencingPuromycin0
(0)