Date published: 2026-4-25

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LGR CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. LGR gene silencers are available as LGR CRISPR/Cas9 Knockout plasmids and LGR Double Nickase Plasmids. LGR CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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LGR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LGR4 CRISPR/Cas9 KO Plasmid (h)

sc-402643hGene KnockoutGFP0
(0)

LGR4 HDR Plasmid (h)

sc-402643-HDRhHomology Directed RepairPuromycin0
(0)

LGR5 CRISPR/Cas9 KO Plasmid (h)

sc-400726hGene KnockoutGFP0
(0)

LGR5 HDR Plasmid (h)

sc-400726-HDRhHomology Directed RepairPuromycin0
(0)

LGR5 Double Nickase Plasmid (h)

sc-400726-NIChGene KnockoutPuromycin0
(0)

LGR5 Double Nickase Plasmid (h2)

sc-400726-NIC-2hGene KnockoutPuromycin0
(0)

LGR5 CRISPR/Cas9 KO Plasmid (m)

sc-420320mGene KnockoutGFP0
(0)

LGR5 HDR Plasmid (m)

sc-420320-HDRmHomology Directed RepairPuromycin0
(0)

LGR5 Double Nickase Plasmid (m)

sc-420320-NICmGene KnockoutPuromycin0
(0)

LGR5 Double Nickase Plasmid (m2)

sc-420320-NIC-2mGene KnockoutPuromycin0
(0)

LGR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LGR4 CRISPR Activation Plasmid (h)

sc-402643-ACThGene ActivationPuro, Blast, Hygro0
(0)

LGR4 CRISPR Activation Plasmid (h2)

sc-402643-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LGR4 CRISPR Activation Plasmid (m)

sc-430724-ACTmGene ActivationPuro, Blast, Hygro0
(0)

LGR4 Lentiviral Activation Particles (m)

sc-430724-LACmGene ActivationPuro, Blast, Hygro0
(0)

LGR5 CRISPR Activation Plasmid (h)

sc-400726-ACThGene ActivationPuro, Blast, Hygro0
(0)

LGR5 CRISPR Activation Plasmid (h2)

sc-400726-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LGR5 CRISPR Activation Plasmid (m)

sc-420320-ACTmGene ActivationPuro, Blast, Hygro0
(0)

LGR5 CRISPR Activation Plasmid (m2)

sc-420320-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

LGR5 Lentiviral Activation Particles (m)

sc-420320-LACmGene ActivationPuro, Blast, Hygro0
(0)

LGR6 CRISPR Activation Plasmid (h)

sc-401443-ACThGene ActivationPuro, Blast, Hygro0
(0)