Lactoferrin inhibitors represent a class of chemical compounds that are primarily designed to interact with and modulate the activity of lactoferrin, a multifunctional glycoprotein found in various bodily fluids, such as milk, saliva, and tears, as well as in neutrophils and other immune cells. Lactoferrin itself plays a vital role in the innate immune system as an antimicrobial protein and also possesses immunomodulatory properties. Inhibitors targeting lactoferrin typically aim to interfere with its functions, either by directly binding to the protein or by modulating its interactions with other molecules. These inhibitors may serve various research and industrial purposes, including elucidating the biochemical roles of lactoferrin in the body or developing strategies to regulate its activity.
The design and development of lactoferrin inhibitors often involve a deep understanding of the protein's structure and function. These compounds may act through various mechanisms, such as competitive binding to lactoferrin's active sites or altering its conformation to disrupt its biological functions. By inhibiting lactoferrin, researchers can gain insights into its involvement in processes like iron homeostasis, immune response, and microbial defense. Additionally, these inhibitors may find applications in fields like biotechnology and food science, where lactoferrin's properties can be harnessed for their functional or nutritional benefits. Overall, lactoferrin inhibitors represent a versatile class of compounds that contribute to our understanding of lactoferrin's role in the body and offer applications in diverse scientific and industrial contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin may inhibit lactoferrin expression through its anti-inflammatory properties and modulation of transcription factors. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin may inhibit lactoferrin expression by suppressing NF-κB activation and interfering with its transcriptional activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein may inhibit lactoferrin expression by modulating estrogen receptor signaling, which affects lactoferrin gene transcription. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
(-)-Epigallocatechin Gallate may inhibit lactoferrin expression through its antioxidant properties and regulation of transcription factors involved. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
L-Sulforaphane may inhibit lactoferrin expression by promoting Nrf2-mediated antioxidant response, leading to reduced transcription. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin may inhibit lactoferrin expression by inhibiting NF-κB activation and modulating inflammatory gene transcription. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $32.00 $42.00 $162.00 $292.00 | 12 | |
Baicalein may inhibit lactoferrin expression by interfering with NF-κB signaling, reducing its transcriptional activity. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin may inhibit lactoferrin expression through its anti-inflammatory effects, impacting transcription factors involved in lactoferrin gene regulation. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine may inhibit lactoferrin expression via modulation of MAPK and NF-κB pathways, affecting the transcriptional regulation of lactoferrin. | ||||||
Piperine | 94-62-2 | sc-205809 sc-205809A | 5 g 25 g | $37.00 $146.00 | 3 | |
Piperine may inhibit lactoferrin expression through its anti-inflammatory properties and potential interference with transcription factor activation. | ||||||