Date published: 2026-4-19

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KLK Inhibitors

Santa Cruz Biotechnology now offers a broad range of KLK Inhibitors for use in various applications. Kallikreins (KLKs) are a subgroup of serine proteases that play significant roles in various physiological processes, including skin desquamation, inflammation, blood pressure regulation, and the processing of growth factors. KLKs are also implicated in pathological conditions, such as cancer progression, where they can influence tumor invasion, metastasis, and angiogenesis. KLK Inhibitors are crucial tools in scientific research, allowing researchers to explore the specific functions of different kallikrein family members and their roles in both normal physiology and disease states. By inhibiting KLK activity, scientists can study the downstream effects on cellular signaling pathways, protein activation cascades, and extracellular matrix remodeling. These inhibitors are widely used in studies focused on understanding the molecular mechanisms of cancer biology, as well as in dermatological research related to skin barrier function and inflammation. Additionally, KLK Inhibitors are valuable in the investigation of their roles in cardiovascular and renal physiology, offering insights into the complex regulatory networks that govern these systems. The availability of these inhibitors has significantly advanced research in fields such as oncology, dermatology, and cardiovascular biology, providing essential tools for dissecting the intricate biological processes mediated by kallikreins. View detailed information on our available KLK Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Camostat mesylate

59721-29-8sc-203867
sc-203867A
sc-203867B
sc-203867C
sc-203867D
sc-203867E
10 mg
50 mg
500 mg
1 g
10 g
100 g
$43.00
$183.00
$312.00
$624.00
$2081.00
$4474.00
5
(0)

Camostat mesylate acts as a potent serine protease inhibitor, exhibiting a unique mechanism of action through its reversible binding to the active site of target enzymes. This interaction alters the enzyme's conformation, impacting substrate accessibility and catalytic efficiency. Its specificity for certain proteases allows for selective modulation of proteolytic pathways, influencing various biological processes. The compound's kinetic profile reveals a rapid association and slower dissociation, underscoring its potential for sustained enzymatic regulation.

Nafamostat mesylate

82956-11-4sc-201307
sc-201307A
10 mg
50 mg
$82.00
$306.00
4
(1)

Nafamostat mesylate functions as a selective inhibitor of serine proteases, characterized by its ability to form stable complexes with target enzymes. This compound exhibits a unique affinity for the active site, leading to conformational changes that hinder substrate binding. Its rapid kinetics facilitate quick inhibition, while the prolonged dissociation rate allows for extended regulatory effects on proteolytic activity. The compound's specificity enhances its role in modulating intricate biochemical pathways.

Gabexate mesylate

56974-61-9sc-215066
5 mg
$100.00
(0)

Gabexate mesylate acts as a potent inhibitor of serine proteases, distinguished by its unique ability to interact with the enzyme's active site through hydrogen bonding and hydrophobic interactions. This compound demonstrates a rapid onset of action, effectively altering enzyme conformation and disrupting substrate access. Its selective binding profile allows for targeted modulation of proteolytic processes, influencing various physiological pathways with precision and efficiency.