KLF7 activators represent a class of chemical compounds that play a pivotal role in the modulation of gene expression and transcriptional regulation within the human body. KLF7, short for Krüppel-like factor 7, is a member of the Krüppel-like family of transcription factors. These factors are crucial in controlling various cellular processes, including cell proliferation, differentiation, and apoptosis, making them pivotal players in the intricate web of molecular mechanisms that govern cell fate and function.
KLF7 activators are small molecules or compounds that specifically target and enhance the activity of the KLF7 transcription factor. These activators function by binding to KLF7 and promoting its ability to bind to DNA, subsequently initiating or repressing the transcription of target genes. The precise mechanisms through which KLF7 activators operate can vary, but their ultimate effect is the fine-tuning of gene expression patterns, which can have profound implications for various biological processes. These compounds have garnered significant interest in the field of molecular biology and cellular research due to their potential to unravel the intricate regulatory networks governing cell development and homeostasis.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a natural compound found in turmeric with anti-inflammatory and antioxidant properties. It activates KLF7 by modulating various signaling pathways and transcription factors that regulate KLF7 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases intracellular cyclic AMP (cAMP) levels by activating adenylate cyclase. Elevated cAMP levels activate KLF7 through cAMP-responsive elements in its promoter region. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a synthetic glucocorticoid that can activate KLF7, likely through binding to glucocorticoid receptors and modulating their transcriptional activity. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
Nicotinamide, a form of vitamin B3, can activate KLF7 through various cellular signaling pathways, although the exact mechanism may vary depending on the context. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Sodium valproate can activate KLF7, likely by inhibiting histone deacetylases (HDACs) and promoting an open chromatin state. | ||||||