KIAA1704 inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the KIAA1704 protein. The KIAA1704 gene, located on human chromosome 17, encodes a protein whose precise function is still under active research, but it is believed to be involved in various cellular processes, including signal transduction and gene expression regulation. By inhibiting this protein, researchers aim to explore its broader role within cellular pathways and its potential impact on key biochemical processes. KIAA1704 inhibitors are designed to bind with high specificity to the protein's active site or key regulatory regions, preventing it from interacting with other cellular components. This inhibition can cause alterations in downstream signaling cascades, making KIAA1704 an attractive subject for fundamental biochemical research.
The study of KIAA1704 inhibitors involves detailed structure-activity relationship (SAR) analysis, where modifications to the chemical structure of these inhibitors help elucidate how the KIAA1704 protein interacts with its inhibitors. Chemical synthesis techniques are utilized to create analogs of known inhibitors, aiming to improve binding affinity, selectivity, and stability. Furthermore, researchers may employ various assays, such as in vitro enzyme assays, to test the effectiveness of different inhibitors in halting KIAA1704 activity. The mechanisms of inhibition are also studied using molecular docking simulations and crystallography to visualize how inhibitors fit within the protein's structure. This deep exploration of the chemical and molecular properties of KIAA1704 inhibitors can significantly advance the understanding of cellular networks and biological systems.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A broad-spectrum protein kinase inhibitor, affecting multiple signaling pathways. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor, impacting protein degradation and the NF-kB pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, affecting cell proliferation and apoptosis. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, influencing cell growth and protein synthesis. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Another MEK inhibitor, specifically blocking MEK1, thus affecting cell growth and apoptosis. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, influencing inflammatory responses and cell stress pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, involved in stress responses and apoptosis. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor, used clinically for certain types of cancer. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
An inhibitor of SERCA, affecting calcium homeostasis. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $74.00 | 256 | |
A broad-spectrum caspase inhibitor, impacting apoptosis pathways. | ||||||