Date published: 2026-4-1

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KIAA0776 Inhibitors

KIAA0776 inhibitors belong to a class of chemical compounds designed to target and modulate the activity of the KIAA0776 protein, also known as C3orf52 or Fam201a. This protein, encoded by the KIAA0776 gene, is relatively understudied but is believed to play a role in various cellular processes, including intracellular trafficking, membrane dynamics, and possibly signal transduction pathways. The development of inhibitors for KIAA0776 stems from the need to elucidate its precise functions within the cell and explore potential applications in biotechnology and basic research.

Chemically, KIAA0776 inhibitors can vary widely, encompassing small molecules or biologics that can selectively bind to the KIAA0776 protein, thereby inhibiting its normal activity. These inhibitors are typically designed with the aim of disrupting the protein's function, either by blocking its active site or interfering with its interaction with other cellular components. The discovery and design of KIAA0776 inhibitors often involve high-throughput screening, structure-based drug design, or other molecular modeling techniques to identify compounds with the desired inhibitory properties. Subsequent testing and optimization help refine these inhibitors for research purposes, shedding light on the protein's role in cellular biology.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Induces Nrf2 by modifying KEAP1 cysteine residues, disrupting the KEAP1-Nrf2 interaction.

CDDO Imidazolide

443104-02-7sc-504719
1 mg
$700.00
(0)

Binds to cysteine residues on KEAP1, modulating the Nrf2 pathway.

Brusatol

14907-98-3sc-507427
5 mg
$148.00
1
(0)

Enhances the degradation of Nrf2, indirectly affecting KEAP1's regulatory role.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Modulates Nrf2 activity by disrupting its interaction with KEAP1.

Oltipraz

64224-21-1sc-205777
sc-205777A
500 mg
1 g
$286.00
$622.00
(1)

Modifies cysteine residues on KEAP1, leading to Nrf2 accumulation and activation.

CDDO Methyl Ester

218600-53-4sc-504720
10 mg
$220.00
(0)

Forms adducts with KEAP1 cysteine residues, promoting Nrf2 activity.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Influences the Nrf2 pathway and may indirectly affect KEAP1's function.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Has been shown to disrupt KEAP1-Nrf2 interaction, consequently enhancing Nrf2 signaling.

t-Butylhydroquinone

1948-33-0sc-202825
10 g
$67.00
4
(1)

Electrophilic compound that can modify KEAP1, leading to Nrf2 activation.

Dimethyl fumarate

624-49-7sc-239774
25 g
$28.00
6
(1)

Modifies KEAP1 cysteine residues, resulting in Nrf2 pathway activation.