Date published: 2026-5-17

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Keratin 42 Inhibitors

Keratin 42 inhibitors represent a class of chemical compounds designed to target and interfere with the activity of Keratin 42, a specific member of the keratin protein family. Keratins are structural proteins that play crucial roles in forming the cytoskeleton of epithelial cells, providing mechanical stability, and contributing to the integrity of tissues such as skin, hair, and nails. Keratin 42, while less extensively studied than some other keratins, likely plays a role in the structural organization and function of specific epithelial cells within the body.

The primary mechanism of action for Keratin 42 inhibitors typically involves their interaction with the Keratin 42 protein or its associated molecules, leading to the disruption of its normal structural and functional properties. By inhibiting Keratin 42, these compounds may potentially affect the organization and function of the epithelial cells in which it is expressed. Researchers studying Keratin 42 inhibitors aim to elucidate the specific roles and functions of Keratin 42 in cellular biology, contributing to our understanding of its significance within the context of tissue integrity and structural support. These inhibitors serve as valuable tools for advancing our knowledge of keratin biology and the contributions of specific keratin isoforms to the structural properties of various epithelial tissues. In this context, they contribute to expanding our understanding of the complex world of cytoskeletal proteins and their roles in maintaining tissue integrity.

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Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$275.00
$474.00
$1639.00
$2497.00
$5344.00
4
(1)

Rocaglamide blocks eukaryotic initiation factor 4A, which is crucial for mRNA unwinding during translation, potentially affecting keratin synthesis.

Ellipticine

519-23-3sc-200878
sc-200878A
10 mg
50 mg
$145.00
$569.00
4
(1)

Ellipticine intercalates with DNA and can inhibit topoisomerase II, leading to broad effects on gene expression, including keratins.