Date published: 2026-2-22

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KCTD3 Activators

The term KCTD3 Activators refers to a specific category of chemical compounds designed to modulate the activity of the KCTD3 gene or protein. KCTD3, or Potassium Channel Tetramerization Domain Containing 3, is a gene that encodes a protein associated with the regulation of ion channels, particularly potassium channels. The precise biological functions and regulatory mechanisms of KCTD3 are subjects of ongoing research within the fields of molecular biology and neuroscience. Activators within the KCTD3 Activators class are typically small molecules or chemical agents strategically engineered to interact with the KCTD3 gene or protein, with the aim of enhancing its expression or influencing its functional capabilities. These activators serve as valuable tools for researchers to manipulate KCTD3-related processes and explore its potential functions in the context of ion channel regulation.

The mechanism of action for KCTD3 Activators may involve various aspects of gene regulation or protein function. These compounds could influence the binding of transcription factors to the promoter region of the KCTD3 gene, potentially increasing its transcriptional activity and leading to elevated KCTD3 gene expression levels. Alternatively, they might affect post-translational modifications or interactions of the KCTD3 protein, such as phosphorylation or protein-protein interactions, which can modulate its stability, function, or subcellular localization within the cell, particularly in the context of regulating potassium channels. Researchers and scientists employ KCTD3 Activators in molecular and cellular biology studies to investigate the role of KCTD3 in ion channel regulation and potential implications in neuronal excitability and cellular physiology. By selectively modulating the gene's activity or protein function, researchers can gain insights into its functions, regulatory mechanisms, and potential involvement in maintaining proper ion channel activity, contributing to a deeper understanding of the molecular processes involving KCTD3 and its significance in cellular biology. Overall, KCTD3 Activators provide valuable tools for exploring the functions and regulatory mechanisms of KCTD3 in the context of ion channel regulation and neuronal physiology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylate cyclase, increasing cAMP levels, which could influence KCTD3 expression through cAMP-dependent signaling pathways involved in ion channel regulation.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid, involved in cellular differentiation and neuronal growth, might upregulate KCTD3 as part of its role in modulating neuronal function and development.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium might influence KCTD3 expression through its effects on signal transduction pathways and ion homeostasis in neurons.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Valproic acid, an HDAC inhibitor and anticonvulsant, could potentially affect KCTD3 expression through its broad effects on gene expression and neuronal excitability.

Kainic acid

487-79-6sc-200454
sc-200454A
sc-200454B
sc-200454C
sc-200454D
5 mg
25 mg
100 mg
1 g
5 g
$87.00
$370.00
$1377.00
$7803.00
$24970.00
12
(1)

Kainic acid, an agonist of glutamate receptors, could induce neuronal activity changes that might upregulate KCTD3 expression as part of the neuronal response to excitotoxicity.

Gabapentin

60142-96-3sc-201481
sc-201481A
sc-201481B
20 mg
100 mg
1 g
$53.00
$94.00
$135.00
7
(1)

Gabapentin, used in neuropathic pain and epilepsy, might affect KCTD3 expression through its modulation of calcium channels and neuronal excitability.

Nifedipine

21829-25-4sc-3589
sc-3589A
1 g
5 g
$59.00
$173.00
15
(1)

Nifedipine, a calcium channel blocker, might indirectly influence KCTD3 expression by altering calcium signaling and potentially affecting ion channel regulation mechanisms.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone, a glucocorticoid, can influence gene expression related to stress responses and inflammation, potentially including KCTD3 as part of its regulatory effects on neuronal cells.

Hydrogen Peroxide

7722-84-1sc-203336
sc-203336A
sc-203336B
100 ml
500 ml
3.8 L
$31.00
$61.00
$95.00
28
(1)

Hydrogen peroxide, as an inducer of oxidative stress, could potentially upregulate KCTD3 as part of the cellular antioxidant defense mechanism, particularly in neurons.