JNK Inhibitors
Items 11 to 13 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BI 78D3 | 883065-90-5 | sc-203840 sc-203840A | 10 mg 50 mg | $204.00 $810.00 | 2 | |
BI 78D3 acts as a JNK inhibitor through its ability to modulate the enzyme's phosphorylation state. Its structural features facilitate unique hydrogen bonding and hydrophobic interactions, which stabilize the enzyme-inhibitor complex. This compound exhibits a non-competitive inhibition mechanism, influencing the allosteric sites and altering the enzyme's activity without directly competing with the substrate. The resulting changes in reaction kinetics can significantly affect downstream signaling cascades. | ||||||
AEG 3482 | 63735-71-7 | sc-202911 | 5 mg | $114.00 | ||
AEG 3482 functions as a JNK inhibitor by selectively disrupting the enzyme's active site interactions. Its unique molecular architecture allows for specific electrostatic interactions that enhance binding affinity. This compound exhibits a mixed inhibition profile, impacting both the active and allosteric sites, which leads to altered substrate turnover rates. The modulation of JNK activity by AEG 3482 can influence critical cellular pathways, showcasing its intricate role in signal transduction. | ||||||
SU 3327 | 40045-50-9 | sc-296430 sc-296430A | 10 mg 50 mg | $169.00 $715.00 | 1 | |
SU 3327 acts as a JNK inhibitor through its ability to form stable complexes with the enzyme, primarily via hydrophobic interactions and hydrogen bonding. Its structural features enable it to preferentially bind to the enzyme's regulatory domain, thereby modulating its conformational dynamics. This compound exhibits competitive inhibition, effectively altering the kinetics of substrate binding and influencing downstream signaling cascades, highlighting its role in cellular response mechanisms. | ||||||