Date published: 2026-4-1

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INSM2 Inhibitors

INSM2 inhibitors are part of a chemical class that targets the INSM2 (insulinoma-associated 2) protein, a protein involved in cellular processes in various organisms. INSM2, though named for its association with insulinoma, has broad implications in the world of cellular biology. The name "inhibitor" typically suggests that the chemicals or molecules in this class hinder or reduce the activity or the function of the protein they target. In the case of INSM2 inhibitors, they are designed to interact and modulate the activity or expression of INSM2, which can influence the downstream cellular events linked to this protein.

The structure and specific mechanism of action of INSM2 inhibitors can vary widely, as is common with many classes of chemicals or drugs. These inhibitors may be small organic molecules, peptides, or even larger biomolecules. Their method of action might involve direct binding to the INSM2 protein, blocking it from fulfilling its normal cellular function. Alternatively, they might operate indirectly, by influencing pathways or other proteins that, in turn, regulate INSM2 activity. Understanding the specifics of these inhibitors, including their physicochemical properties, molecular interactions, and off-target effects, is essential for researchers in fields that study INSM2 and its associated cellular processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Imatinib mesylate

220127-57-1sc-202180
sc-202180A
25 mg
100 mg
$45.00
$111.00
61
(1)

Targets tyrosine kinases, especially BCR-ABL in leukemia.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

Stabilizes microtubules, disrupting cell division.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$57.00
$100.00
$250.00
129
(3)

Inhibits multiple kinases, including VEGFR and RAF.

Tamoxifen

10540-29-1sc-208414
2.5 g
$272.00
18
(2)

Blocks estrogen receptors in breast cancer cells.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$94.00
$213.00
33
(5)

Inhibits dihydrofolate reductase, disrupting DNA synthesis.

Lapatinib

231277-92-2sc-353658
100 mg
$420.00
32
(1)

Targets EGFR and HER2 kinases in breast cancer.

Gefitinib

184475-35-2sc-202166
sc-202166A
sc-202166B
sc-202166C
100 mg
250 mg
1 g
5 g
$63.00
$114.00
$218.00
$349.00
74
(2)

Blocks EGFR kinase activity in non-small cell lung cancer.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

Inhibits proteasome, leading to cell cycle arrest.

Vemurafenib

918504-65-1sc-364643
sc-364643A
10 mg
50 mg
$117.00
$423.00
11
(1)

Selectively targets mutated BRAF in melanoma.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$70.00
$145.00
51
(1)

Inhibits multiple kinases, including BCR-ABL and SRC.