ILPIP inhibitors target and inhibit the activity of the ILPIP protein, also known as Inhibitor of IL-1β Post-Translational Modification. ILPIP is an enzyme that plays a crucial role in the post-translational modification of the interleukin-1β (IL-1β) protein, a key mediator in inflammatory responses. The function of ILPIP involves the regulation of IL-1β maturation and secretion, which are critical in the body's immune response. The structure of ILPIP is characterized by specific domains that facilitate its enzymatic activity, including the recognition and modification of IL-1β. The ability of ILPIP to modulate IL-1β activity makes it a target of interest for the development of inhibitors that can specifically interact with and inhibit its function, thereby influencing the IL-1β mediated pathways.
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