Date published: 2026-4-24

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IL-18R Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of IL-18R monoclonal antibodies for investigating the role of IL-18 receptor in various biological processes. IL-18R monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The IL-18 receptor is crucial for mediating the effects of IL-18, a pro-inflammatory cytokine involved in the immune response. IL-18R plays a significant role in the activation of T cells and natural killer (NK) cells, contributing to the body's defense against infections and tumors. Dysregulation of IL-18R signaling has been implicated in various inflammatory diseases and conditions, making it an important target for therapeutic intervention. IL-18R monoclonal antibodies enable researchers to explore immune system regulation and cellular signaling pathways. Understanding IL-18R function and expression patterns helps advance knowledge in immunology and inflammation research. Investigating IL-18R mechanisms provides insights into potential therapeutic strategies for inflammatory disorders. Santa Cruz Biotechnology monoclonal antibodies for IL-18R support researchers in advancing scientific understanding of immune system regulation and disease mechanisms.

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IL-18R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-18Rβ Antibody (48986)

sc-80050mouse IgG2b(h)WB, FCMh

new

(2)

IL-18R Antibody (DB08)

sc-80051rat IgG2a(m)WBm, r
2
(0)

IL-18R CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-18R CRISPR/Cas9 KO Plasmid (h)

sc-405214hGene KnockoutGFP0
(0)

IL-18R HDR Plasmid (h)

sc-405214-HDRhHomology Directed RepairPuromycin0
(0)

IL-18R CRISPR/Cas9 KO Plasmid (m)

sc-421103mGene KnockoutGFP0
(0)

IL-18R HDR Plasmid (m)

sc-421103-HDRmHomology Directed RepairPuromycin0
(0)

IL-18Rβ CRISPR/Cas9 KO Plasmid (m)

sc-421095mGene KnockoutGFP0
(0)

IL-18R CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-18R CRISPR Activation Plasmid (h)

sc-405214-ACThGene ActivationPuro, Blast, Hygro0
(0)

IL-18R CRISPR Activation Plasmid (h2)

sc-405214-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IL-18Rβ CRISPR Activation Plasmid (h)

sc-411213-ACThGene ActivationPuro, Blast, Hygro0
(0)

IL-18R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-18R siRNA (h)

sc-45285hGene SilencingN/A
1
(0)

IL-18R shRNA Plasmid (h)

sc-45285-SHhGene SilencingPuromycin
1
(0)

IL-18R shRNA (h) Lentiviral Particles

sc-45285-VhGene SilencingPuromycin
1
(0)

IL-18R siRNA (m)

sc-45286mGene SilencingN/A0
(0)

IL-18R shRNA Plasmid (m)

sc-45286-SHmGene SilencingPuromycin0
(0)

IL-18R shRNA (m) Lentiviral Particles

sc-45286-VmGene SilencingPuromycin0
(0)

IL-18Rβ siRNA (h)

sc-94362hGene SilencingN/A0
(0)

IL-18Rβ shRNA Plasmid (h)

sc-94362-SHhGene SilencingPuromycin0
(0)

IL-18Rβ shRNA (h) Lentiviral Particles

sc-94362-VhGene SilencingPuromycin0
(0)

IL-18Rβ siRNA (m)

sc-146208mGene SilencingN/A0
(0)

IL-18Rβ shRNA Plasmid (m)

sc-146208-SHmGene SilencingPuromycin0
(0)

IL-18Rβ shRNA (m) Lentiviral Particles

sc-146208-VmGene SilencingPuromycin0
(0)