Date published: 2026-5-5

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IKK gamma Inhibitors

Santa Cruz Biotechnology now offers a broad range of IKK gamma Inhibitors for use in various applications. IKK gamma Inhibitors are essential tools for studying the function and regulation of IκB kinase gamma (IKKγ), also known as NEMO (NF-κB Essential Modulator). IKKγ is a crucial regulatory subunit of the IKK complex, which plays a significant role in activating the NF-κB signaling pathway. In scientific research, IKK gamma Inhibitors are used to explore the downstream effects of IKKγ inhibition on gene expression, cytokine production, and cellular responses to stress and pathogens. These inhibitors help explain the role of IKKγ in modulating immune and inflammatory responses, providing insights into how IKKγ activity impacts the translocation of NF-κB to the nucleus and subsequent transcription of target genes. Additionally, these inhibitors are valuable in high-throughput screening assays aimed at discovering new modulators of IKKγ activity, aiding in the identification of novel regulatory mechanisms and potential research targets. The use of IKK gamma Inhibitors supports the development of experimental models to dissect the complex signaling networks involving IKKγ and NF-κB, enhancing our understanding of cellular regulation and adaptation. View detailed information on our available IKK gamma Inhibitors by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wedelolactone

524-12-9sc-200648
sc-200648A
1 mg
5 mg
$110.00
$337.00
8
(0)

Wedelolactone functions as an IKK gamma modulator, exhibiting unique binding dynamics through its ability to form specific interactions with the enzyme's active site. Its structural conformation facilitates distinct electrostatic and hydrophobic interactions, promoting selective inhibition. The compound's reaction kinetics indicate a rapid onset of action, which may lead to immediate alterations in the NF-kB signaling pathway. Additionally, its solubility properties could affect cellular localization and interaction with other signaling molecules.

MRT67307

1190378-57-4sc-507433
10 mg
$234.00
(0)