HXK Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-Mannoheptulose | 3615-44-9 | sc-221499A sc-221499 sc-221499B sc-221499C sc-221499D | 25 mg 50 mg 100 mg 250 mg 500 mg | $255.00 $465.00 $897.00 $1785.00 $3580.00 | 1 | |
D-Mannoheptulose is a unique sugar that acts as a hexokinase inhibitor, selectively modulating glucose metabolism. Its structural conformation allows it to compete with glucose for binding sites on hexokinase, altering enzyme kinetics and reducing ATP production. This interaction influences metabolic pathways, particularly in energy regulation. The compound's distinct stereochemistry enhances its affinity for the enzyme, leading to significant shifts in cellular energy dynamics and metabolic flux. | ||||||
Lauroylsarcosine, Sodium Salt | 137-16-6 | sc-280907 | 1 g | $172.00 | ||
Lauroylsarcosine, Sodium Salt, exhibits intriguing properties as a hexokinase modulator, influencing glucose phosphorylation. Its amphiphilic nature facilitates unique interactions with lipid membranes, potentially altering enzyme accessibility. The compound's ability to form micelles may enhance local concentrations of glucose, impacting reaction kinetics. Additionally, its structural features allow for competitive inhibition, subtly shifting metabolic pathways and energy homeostasis within cells. | ||||||
D-Glucose 6-phosphate disodium salt | 3671-99-6 | sc-221488 sc-221488A sc-221488B | 10 mg 1 g 25 g | $38.00 $66.00 $1102.00 | 1 | |
D-Glucose 6-phosphate disodium salt serves as a crucial substrate for hexokinase, playing a pivotal role in glycolysis. Its phosphorylated form enhances the stability of glucose, promoting efficient enzymatic conversion. The compound's ionic nature facilitates solubility in aqueous environments, allowing for rapid diffusion and interaction with hexokinase. This dynamic interaction can modulate enzyme activity, influencing metabolic flux and energy production in cellular processes. | ||||||
Lonidamine | 50264-69-2 | sc-203115 sc-203115A | 5 mg 25 mg | $103.00 $357.00 | 7 | |
Lonidamine exhibits unique interactions with hexokinase, acting as a competitive inhibitor that alters the enzyme's affinity for glucose. Its structural conformation allows for specific binding to the active site, disrupting normal substrate turnover. This modulation of reaction kinetics can lead to a decrease in glycolytic flux, impacting energy metabolism. Additionally, its lipophilic characteristics enhance membrane permeability, influencing cellular uptake and distribution within metabolic pathways. | ||||||
D-Glucose-6-phosphate monosodium salt | 54010-71-8 | sc-210728 sc-210728A | 1 g 5 g | $66.00 $240.00 | 3 | |
D-Glucose-6-phosphate monosodium salt plays a crucial role in cellular metabolism as a substrate for hexokinase, facilitating the phosphorylation of glucose. Its unique phosphate group enhances binding affinity, promoting efficient catalysis. The compound participates in various metabolic pathways, including glycolysis and the pentose phosphate pathway, influencing energy production and biosynthetic processes. Its solubility in aqueous environments supports rapid cellular uptake and integration into metabolic networks. | ||||||