hnRNP UL1 is a protein that belongs to the heterogeneous nuclear ribonucleoproteins family, which is involved in the processing of pre-mRNA in the nucleus. It plays a role in various aspects of mRNA metabolism, including splicing, stability, transport, and possibly transcriptional regulation. Activators of hnRNP UL1 enhance the protein's natural function, potentially influencing these critical cellular processes.
Direct activators of hnRNP UL1 interact with the protein itself, potentially binding to specific domains to induce a conformational change that increases its binding affinity to RNA substrates or promotes interactions with other proteins involved in RNA metabolism. This direct interaction could enhance the protein's activity, facilitating more efficient splicing or processing of pre-mRNA, for instance. Indirect activators work by upregulating the expression of the HNRNPUL1 gene, leading to increased protein levels within the cell. Alternatively, they could modulate the post-translational modifications of hnRNP UL1, such as phosphorylation or ubiquitination, which can alter the protein's function, localization, or interaction with other molecules. Such indirect mechanisms might operate through signaling pathways that ultimately affect hnRNP UL1.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $38.00 $74.00 | 9 | |
ATP provides the energy for many cellular processes including RNA binding and processing, where hnRNP UL1 is involved. Higher ATP levels can indirectly activate hnRNP UL1 by promoting its function in RNA processing. | ||||||
Uridine-5′-triphosphate, Trisodium Salt | 19817-92-6 | sc-301964 sc-301964A | 50 mg 1 g | $86.00 $118.00 | 2 | |
UTP is involved in the synthesis of RNA. Its abundance can indirectly activate hnRNP UL1 by promoting the production of RNA, the substrate with which hnRNP UL1 interacts. | ||||||
Guanosine 5′-Triphosphate, Disodium Salt | 56001-37-7 | sc-295030 sc-295030A | 50 mg 250 mg | $163.00 $321.00 | ||
GTP is critical for RNA helicase activity. Its availability can indirectly activate hnRNP UL1 by promoting RNA unwinding and subsequent RNA processing mechanisms. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
Magnesium ions are necessary for RNA helicase activity and can indirectly activate hnRNP UL1 by promoting RNA unwinding and subsequent RNA processing mechanisms. | ||||||
Sodium Chloride | 7647-14-5 | sc-203274 sc-203274A sc-203274B sc-203274C | 500 g 2 kg 5 kg 10 kg | $18.00 $23.00 $35.00 $65.00 | 15 | |
Sodium ions are necessary for the stability and proper functioning of many proteins, including hnRNP UL1. Increased levels can indirectly activate hnRNP UL1 by maintaining its stability and functionality. | ||||||
Potassium Chloride | 7447-40-7 | sc-203207 sc-203207A sc-203207B sc-203207C | 500 g 2 kg 5 kg 10 kg | $25.00 $56.00 $104.00 $183.00 | 5 | |
Potassium ions are necessary for the stability and proper functioning of many proteins, including hnRNP UL1. Increased levels can indirectly activate hnRNP UL1 by maintaining its stability and functionality. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin inhibits RNA Polymerase II, leading to the accumulation of pre-mRNA, which is the substrate for hnRNP UL1. This can indirectly activate hnRNP UL1 by increasing substrate availability for RNA processing. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA Polymerase II, leading to the accumulation of pre-mRNA, which is the substrate for hnRNP UL1. This can indirectly activate hnRNP UL1 by increasing substrate availability for RNA processing. | ||||||