Date published: 2026-1-9

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HMGCL Antibodies

Santa Cruz Biotechnology features a diverse variety of HMGCL monoclonal antibodies for research in biochemistry and molecular biology. HMGCL monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HMGCL, or 3-hydroxy-3-methylglutaryl-CoA lyase, plays a crucial role in the metabolism of ketone bodies and amino acids, making it essential for energy production during fasting states. Its proper function is vital for maintaining metabolic homeostasis, and mutations in the HMGCL gene can lead to metabolic disorders such as HMG-CoA lyase deficiency. Understanding HMGCL function in cellular metabolism can provide insights into various physiological and pathological conditions. Researchers studying HMGCL can uncover new pathways and mechanisms involved in metabolic regulation. HMGCL research has significant implications for understanding metabolic disorders and developing potential therapeutic strategies. Investigating HMGCL expression patterns helps reveal its role in different tissues and developmental stages. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of metabolic processes and contribute to breakthrough discoveries in human health.

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HMGCL Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HMGCL Antibody (63Z)

sc-100548mouse IgG2a κ1-326 (h)WB, IP, ELISAh
2
(2)

HMGCL CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HMGCL CRISPR/Cas9 KO Plasmid (h)

sc-403841hGene KnockoutGFP0
(0)

HMGCL HDR Plasmid (h)

sc-403841-HDRhHomology Directed RepairPuromycin0
(0)

HMGCL Double Nickase Plasmid (h)

sc-403841-NIChGene KnockoutPuromycin0
(0)

HMGCL Double Nickase Plasmid (h2)

sc-403841-NIC-2hGene KnockoutPuromycin0
(0)

HMGCL CRISPR/Cas9 KO Plasmid (m)

sc-420876mGene KnockoutGFP0
(0)

HMGCL HDR Plasmid (m)

sc-420876-HDRmHomology Directed RepairPuromycin0
(0)

HMGCL Double Nickase Plasmid (m)

sc-420876-NICmGene KnockoutPuromycin0
(0)

HMGCL Double Nickase Plasmid (m2)

sc-420876-NIC-2mGene KnockoutPuromycin0
(0)

HMGCL CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HMGCL CRISPR Activation Plasmid (h)

sc-403841-ACThGene ActivationPuro, Blast, Hygro0
(0)

HMGCL CRISPR Activation Plasmid (h2)

sc-403841-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

HMGCL Lentiviral Activation Particles (h)

sc-403841-LAChGene ActivationPuro, Blast, Hygro0
(0)

HMGCL Lentiviral Activation Particles (h2)

sc-403841-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

HMGCL CRISPR Activation Plasmid (m)

sc-420876-ACTmGene ActivationPuro, Blast, Hygro0
(0)

HMGCL CRISPR Activation Plasmid (m2)

sc-420876-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

HMGCL Lentiviral Activation Particles (m)

sc-420876-LACmGene ActivationPuro, Blast, Hygro0
(0)

HMGCL Lentiviral Activation Particles (m2)

sc-420876-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

HMGCL siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HMGCL siRNA (h)

sc-78794hGene SilencingN/A0
(0)

HMGCL shRNA Plasmid (h)

sc-78794-SHhGene SilencingPuromycin0
(0)

HMGCL shRNA (h) Lentiviral Particles

sc-78794-VhGene SilencingPuromycin0
(0)

HMGCL siRNA (m)

sc-146051mGene SilencingN/A
1
(0)

HMGCL shRNA Plasmid (m)

sc-146051-SHmGene SilencingPuromycin
1
(0)

HMGCL shRNA (m) Lentiviral Particles

sc-146051-VmGene SilencingPuromycin
1
(0)