Date published: 2026-4-4

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HIF-1 α Antibodies

Santa Cruz Biotechnology provides a broad selection of HIF-1 α monoclonal antibodies for research focused on understanding the hypoxia-inducible factor pathway. HIF-1 α Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HIF-1 α plays a critical role in cellular responses to low oxygen levels, regulating genes involved in angiogenesis, metabolism, and cell survival. HIF-1 α dysregulation is implicated in various diseases, including cancer, making it a significant target for therapeutic intervention. Understanding the function of HIF-1 α is essential for advancing research in cancer biology and other hypoxia-related conditions. Researchers can explore the complex mechanisms of oxygen sensing and cellular adaptation through detailed analysis of HIF-1 α expression and activity. Investigation of HIF-1 α signaling pathways provides valuable insights into disease progression and potential treatment strategies. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to make meaningful contributions to understanding hypoxia-related pathologies.

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HIF-1 α Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HIF1a Antibody (28b)

sc-13515mouse IgG1 κ329-530 (h)WB, IP, IF, IHC(P)m, r, h
288
(90)

HIF1a Antibody (H1alpha 67)

sc-53546mouse IgG2b κ432-528 (h)WB, IP, IF, IHC(P)m, r, h
194
(24)

HIF1a Antibody (3C144)

sc-71247mouse IgG1 κ329-530 (h)WB, IP, IFm, r, h
18
(2)

HIF-1 α CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HIF1a CRISPR/Cas9 KO Plasmid (h2)

sc-400036-KO-2hGene KnockoutGFP
1
(0)

HIF1a HDR Plasmid (h2)

sc-400036-HDR-2hHomology Directed RepairPuromycin
1
(0)

HIF1a Double Nickase Plasmid (h)

sc-400036-NIChGene KnockoutPuromycin
1
(0)

HIF1a Double Nickase Plasmid (h2)

sc-400036-NIC-2hGene KnockoutPuromycin
1
(0)

HIF1a CRISPR/Cas9 KO Plasmid (m2)

sc-420856-KO-2mGene KnockoutGFP
1
(0)

HIF1a HDR Plasmid (m2)

sc-420856-HDR-2mHomology Directed RepairPuromycin
1
(0)

HIF1a Double Nickase Plasmid (m)

sc-420856-NICmGene KnockoutPuromycin
1
(0)

HIF1a Double Nickase Plasmid (m2)

sc-420856-NIC-2mGene KnockoutPuromycin
1
(0)

HIF-1 α CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HIF1a CRISPR Activation Plasmid (h)

sc-400036-ACThGene ActivationPuro, Blast, Hygro
1
(0)

HIF1a CRISPR Activation Plasmid (h2)

sc-400036-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

HIF1a Lentiviral Activation Particles (h)

sc-400036-LAChGene ActivationPuro, Blast, Hygro
1
(0)

HIF1a CRISPR Activation Plasmid (m)

sc-420856-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

HIF1a CRISPR Activation Plasmid (m2)

sc-420856-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

HIF1a Lentiviral Activation Particles (m)

sc-420856-LACmGene ActivationPuro, Blast, Hygro
1
(0)

HIF-1 α siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HIF1a siRNA (h)

sc-35561hGene SilencingN/A
195
(4)

HIF1a siRNA (h2)

sc-44225hGene SilencingN/A
21
(0)

HIF1a shRNA Plasmid (h)

sc-35561-SHhGene SilencingPuromycin
195
(4)

HIF1a shRNA Plasmid (h2)

sc-44225-SHhGene SilencingPuromycin
21
(0)

HIF1a shRNA (h) Lentiviral Particles

sc-35561-VhGene SilencingPuromycin
195
(4)

HIF1a shRNA (h2) Lentiviral Particles

sc-44225-VhGene SilencingPuromycin
21
(0)

HIF1a siRNA (m)

sc-35562mGene SilencingN/A
62
(0)

HIF1a siRNA (m2)

sc-44308mGene SilencingN/A
3
(0)

HIF1a shRNA Plasmid (m)

sc-35562-SHmGene SilencingPuromycin
62
(0)

HIF1a shRNA Plasmid (m2)

sc-44308-SHmGene SilencingPuromycin
3
(0)

HIF1a shRNA (m) Lentiviral Particles

sc-35562-VmGene SilencingPuromycin
62
(0)

HIF1a shRNA (m2) Lentiviral Particles

sc-44308-VmGene SilencingPuromycin
3
(0)

HIF1a siRNA (r)

sc-45919rGene SilencingN/A
32
(0)

HIF1a shRNA Plasmid (r)

sc-45919-SHrGene SilencingPuromycin
32
(0)

HIF1a shRNA (r) Lentiviral Particles

sc-45919-VrGene SilencingPuromycin
32
(0)

HIF1a siRNA (chicken)

sc-156142avianGene SilencingN/A
1
(0)

HIF1a shRNA Plasmid (chicken)

sc-156142-SHchickenGene SilencingPuromycin
1
(0)

HIF1a shRNA (chicken) Lentiviral Particles

sc-156142-VchickenGene SilencingPuromycin
1
(0)

HIF1a siRNA (bovine)

sc-270450bovineGene SilencingN/A
1
(0)

HIF1a shRNA Plasmid (bovine)

sc-270450-SHbovineGene SilencingPuromycin
1
(0)

HIF1a shRNA (bovine) Lentiviral Particles

sc-270450-VbovineGene SilencingPuromycin
1
(0)