Date published: 2026-4-5

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HFE Antibodies

Santa Cruz Biotechnology features a diverse variety of HFE monoclonal antibodies for studying HFE protein, which plays a crucial role in iron homeostasis and regulation within the body. HFE monoclonal antibodies support various research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HFE protein regulates iron absorption in the intestine and is implicated in hereditary hemochromatosis, a condition that can lead to iron overload and associated organ damage. Understanding HFE protein function is vital for developing therapeutic strategies for iron-related disorders. Research into HFE protein has revealed its significant impact on maintaining proper iron levels throughout the body. Investigating HFE protein interactions helps scientists uncover new pathways in iron metabolism regulation. Recent studies have highlighted the importance of HFE protein in preventing excessive iron accumulation in vital organs. Santa Cruz Biotechnology monoclonal antibodies for HFE protein research enable scientists to advance our understanding of iron-related diseases and potential treatments.

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HFE Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HFE Antibody (C-12)

sc-514405mouse IgG1 κ210-263 (h)WB, IP, IF, ELISAm, r, h
3
(3)

HFE Antibody (44-H)

sc-130375mouse IgG1 κ115-206 (h)WB, IF, ELISAh
1
(2)

HFE CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HFE CRISPR/Cas9 KO Plasmid (h)

sc-403695hGene KnockoutGFP0
(0)

HFE HDR Plasmid (h)

sc-403695-HDRhHomology Directed RepairPuromycin0
(0)

HFE Double Nickase Plasmid (h)

sc-403695-NIChGene KnockoutPuromycin0
(0)

HFE Double Nickase Plasmid (h2)

sc-403695-NIC-2hGene KnockoutPuromycin0
(0)

HFE CRISPR/Cas9 KO Plasmid (m)

sc-420841mGene KnockoutGFP0
(0)

HFE HDR Plasmid (m)

sc-420841-HDRmHomology Directed RepairPuromycin0
(0)

HFE CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HFE CRISPR Activation Plasmid (h)

sc-403695-ACThGene ActivationPuro, Blast, Hygro0
(0)

HFE CRISPR Activation Plasmid (m)

sc-420841-ACTmGene ActivationPuro, Blast, Hygro0
(0)

HFE CRISPR Activation Plasmid (m2)

sc-420841-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

HFE siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HFE siRNA (h)

sc-43832hGene SilencingN/A0
(1)

HFE shRNA Plasmid (h)

sc-43832-SHhGene SilencingPuromycin0
(1)

HFE shRNA (h) Lentiviral Particles

sc-43832-VhGene SilencingPuromycin0
(1)