HELIC1 Activators
HELIC1 Activators includes various compounds that can indirectly influence the activity of HELIC1, a helicase involved in DNA replication and repair. These compounds primarily target pathways and mechanisms related to DNA damage response, repair processes, and helicase activity, which are essential for maintaining genomic stability.
PARP inhibitors, like Olaparib, target poly (ADP-ribose) polymerase enzymes involved in DNA repair. By affecting these pathways, they could indirectly modulate the activity of HELIC1, which is involved in similar processes. ATR and ATM inhibitors, such as VE-821 and KU-55933, respectively, target kinases critical in the DNA damage response, influencing HELIC1 function. DNA-PK inhibitors, like NU7441, focus on DNA-dependent protein kinase involved in DNA repair pathways, which may have implications for HELIC1 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
PARP inhibitors affect DNA repair pathways and could indirectly influence HELIC1 activity. | ||||||
VE 821 | 1232410-49-9 | sc-475878 | 10 mg | $360.00 | ||
ATR inhibitors target the ATR kinase involved in DNA damage response, potentially impacting HELIC1 function. | ||||||
ATM Kinase Inhibitor | 587871-26-9 | sc-202963 | 2 mg | $110.00 | 28 | |
ATM inhibitors affect the DNA damage response pathway, potentially influencing HELIC1 activity. | ||||||
NU 7441 | 503468-95-9 | sc-208107 | 5 mg | $357.00 | 10 | |
DNA-PK inhibitors target DNA-dependent protein kinase in DNA repair, potentially affecting HELIC1. | ||||||
UCN-01 | 112953-11-4 | sc-202376 | 500 µg | $251.00 | 10 | |
CHK1 inhibitors target a key kinase in DNA damage response, potentially impacting HELIC1 function. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
HSP90 inhibitors can affect protein folding and stability, potentially impacting HELIC1 function. | ||||||