Date published: 2026-2-2

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HDAC Inhibitors

Santa Cruz Biotechnology now offers a broad range of HDAC Inhibitors for use in various applications. HDAC inhibitors, or histone deacetylase inhibitors, are a class of compounds that play a crucial role in the regulation of gene expression through the modulation of chromatin structure. By inhibiting the activity of histone deacetylases, these compounds promote the acetylation of histone proteins, leading to a more open chromatin configuration and facilitating the transcription of specific genes. This regulatory mechanism is essential in various biological processes, including cell cycle control, differentiation, and response to environmental cues. In scientific research, HDAC inhibitors are invaluable tools for studying epigenetic modifications and their effects on gene expression. They are widely used in molecular biology to dissect signaling pathways and understand the complex interactions between DNA, histones, and other chromatin-associated proteins. Researchers employ HDAC inhibitors to explore the epigenetic landscape in various cell types, offering insights into fundamental biological processes and potential applications in biotechnology. View detailed information on our available HDAC Inhibitors by clicking on the product name.

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Isonipecotic acid

498-94-2sc-280859
100 g
$85.00
(0)

Isonipecotic acid acts as a histone deacetylase (HDAC) inhibitor through its unique ability to form hydrogen bonds with key amino acid residues in the enzyme's active site. This interaction stabilizes the enzyme-substrate complex, resulting in a modified reaction kinetics that slows deacetylation processes. Additionally, its cyclic structure contributes to a distinct conformational flexibility, allowing for enhanced binding affinity and specificity, which can influence gene expression regulation.