GPR21 Activators
G Protein-Coupled Receptor 21 (GPR21) is a protein in humans that is encoded by the GPR21 gene. This protein is part of the large G protein-coupled receptors (GPCRs) family, which plays a vital role in many different biological processes by transmitting signals across cell membranes.
GPCRs bind to specific molecules outside the cell (ligands), causing a change in the receptor's shape and triggering a series of events inside the cell. These intracellular events often involve the activation of G proteins, leading to various cellular responses.While there is limited information about the precise role of GPR21, some studies suggest it may be involved in metabolic processes. A study in mice showed that deletion of the GPR21 gene resulted in improved glucose tolerance and insulin sensitivity, suggesting a potential role in glucose homeostasis and insulin signaling.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Enhances adenylate cyclase activity, increasing cAMP levels, which can modulate GPCR signaling. | ||||||
Pilocarpine | 92-13-7 | sc-479256 | 100 mg | $255.00 | 1 | |
A muscarinic acetylcholine receptor agonist, influencing GPCR-mediated neuronal signaling. | ||||||
Carbachol | 51-83-2 | sc-202092 sc-202092A sc-202092C sc-202092D sc-202092B sc-202092E | 1 g 10 g 25 g 50 g 100 g 250 g | $122.00 $281.00 $388.00 $683.00 $1428.00 $3060.00 | 12 | |
Another muscarinic agonist, can affect GPCR signaling indirectly through muscarinic receptors. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
As a neurotransmitter, it can modulate GPCR signaling through dopamine receptors. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Activates histamine receptors, which are GPCRs, potentially influencing related pathways. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $297.00 $577.00 | ||
As a major excitatory neurotransmitter, it can influence GPCR signaling through glutamate receptors. | ||||||
3-(2-Aminoethyl)-1H-indol-5-ol | 50-67-9 | sc-298707 | 1 g | $530.00 | 3 | |
Through its action on serotonin receptors (GPCRs), it can modulate GPCR-related pathways. | ||||||