Gm749 Activators
Colipase-like 2 Activators encompass a variety of chemical compounds that influence different aspects of lipid metabolism, a pathway in which colipase-like 2 is directly involved. Chemicals such as AICAR and Forskolin target the AMPK and PKA pathways respectively, which are known to regulate lipid metabolism processes. Activation of these pathways can lead to an increase in fatty acid oxidation and other lipid processing activities, potentially enhancing the functional demand for colipase-like 2. Additionally, the engagement of PPARs by compounds like Oleoylethanolamide, Bezafibrate, GW7647, L-165,041, Rosiglitazone, and Pioglitazone can lead to upregulation of genes involved in lipid metabolism. As colipase-like 2 is implicated in lipid digestion, the activation of these nuclear receptors can enhance the requirement for colipase-like 2's activity to facilitate efficient lipid processing within the cell.
Moreover, SIRT1 activators like SRT1720 and Nicotinamide riboside can improve lipid metabolism through deacetylation of target proteins, which can have a downstream effect on enhancing the activity of colipase-like 2. Genistein, with its ability to modulate PPARs and SIRT1 activity, also stands as a potential enhancer of colipase-like 2 activity due to its influence on lipid metabolism.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR is an activator of AMP-activated protein kinase (AMPK). Activation of AMPK can lead to enhanced fatty acid oxidation, which may increase the demand for colipase-like 2 in lipid digestion processes. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels. Elevated cAMP can enhance protein kinase A (PKA) activity, which can phosphorylate target proteins involved in lipid metabolism, potentially enhancing the activity of colipase-like 2. | ||||||
Oleylethanolamide | 111-58-0 | sc-201400 sc-201400A | 10 mg 50 mg | $88.00 $190.00 | 1 | |
Oleoylethanolamide is a naturally occurring lipid that activates peroxisome proliferator-activated receptor alpha (PPAR-alpha). PPAR-alpha activation can upregulate lipid metabolism genes, potentially increasing the functional demand for colipase-like 2. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
Bezafibrate is a PPAR pan-agonist, which can enhance the transcription of genes involved in lipid metabolism, potentially increasing the functional activity of colipase-like 2 in fat digestion. | ||||||
GW 7647 | 265129-71-3 | sc-203068A sc-203068 sc-203068B sc-203068C | 1 mg 5 mg 10 mg 25 mg | $48.00 $167.00 $262.00 $648.00 | 6 | |
GW7647 is a potent PPAR-alpha agonist. By stimulating PPAR-alpha, it can increase the catabolism of fatty acids, potentially enhancing the activity of colipase-like 2. | ||||||
L-165041 | 79558-09-1 | sc-203094 | 5 mg | $153.00 | ||
L-165,041 is a PPAR-delta agonist, which can upregulate genes involved in lipid metabolism and could thereby enhance the functional activity of colipase-like 2. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Rosiglitazone is a PPAR-gamma agonist, which can promote adipocyte differentiation and potentially increase the role of colipase-like 2 in lipid processing. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $193.00 $357.00 | 13 | |
SRT1720 is an activator of SIRT1, which can enhance lipid metabolism through deacetylation of target proteins, potentially enhancing the activity of colipase-like 2. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
Nicotinamide riboside is a precursor of NAD+ and can activate SIRT1. SIRT1 activation can lead to improved lipid metabolism, which may increase the functional activity of colipase-like 2. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Pioglitazone is a PPAR-gamma agonist, which can enhance glucose and lipid metabolism, potentially increasing the demand for colipase-like 2's role in lipid processing. | ||||||