Date published: 2026-3-3

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Gm1679 Inhibitors

The term LRCOL1 Inhibitors would refer to a class of compounds that attenuate the function of the human protein LRCOL1. As LRCOL1 is suggested to be an enzyme activator, the inhibitors would likely target the interaction between LRCOL1 and the enzymes it activates, potentially through competitive binding or allosteric modulation. These inhibitors could also affect the expression levels, secretion, or stability of LRCOL1 in the extracellular region.

In the context of LRCOL1's activity, inhibitors might influence the enzymatic processes involved in the digestion of food. For instance, if LRCOL1 activates lipases, compounds that inhibit lipases could reduce the overall effect of LRCOL1. Similarly, if LRCOL1 is part of a cascade of reactions in lipid or carbohydrate metabolism, compounds that alter these metabolic pathways might serve as indirect inhibitors. These could include molecules that affect the absorption, synthesis, or breakdown of macronutrients in the gut.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lipase Inhibitor, THL

96829-58-2sc-203108
50 mg
$52.00
7
(1)

Orlistat is a lipase inhibitor that binds covalently to the serine residue of the active site of gastric and pancreatic lipases, reducing their activity.

Citilistat

282526-98-1sc-358100
sc-358100A
250 mg
1 g
$47.00
$104.00
(0)

Cetilistat is another lipase inhibitor that acts in a similar fashion to Orlistat, potentially reducing the activity of lipases that LRCOL1 may activate.

Ezetimibe

163222-33-1sc-205690
sc-205690A
25 mg
100 mg
$96.00
$241.00
12
(2)

Ezetimibe works by inhibiting the absorption of cholesterol in the intestine, which could indirectly affect the enzymatic activity that LRCOL1 is hypothesized to enhance.

Chitosan

9012-76-4sc-221421
sc-221421A
sc-221421B
sc-221421D
sc-221421C
10 g
25 g
100 g
8 kg
500 g
$41.00
$55.00
$135.00
$3339.00
$298.00
6
(1)

Chitosan is known to bind lipids and could thereby interfere with the interaction between lipases and their activators, potentially including LRCOL1.

Linoleic Acid

60-33-3sc-200788
sc-200788A
sc-200788B
sc-200788C
100 mg
1 g
5 g
25 g
$34.00
$64.00
$166.00
$281.00
4
(2)

Known to modulate lipid metabolism, which could indirectly influence the enzymatic processes LRCOL1 may activate.

Chromium Picolinate

14639-25-9sc-204685
sc-204685A
5 g
25 g
$214.00
$667.00
1
(0)

This compound is thought to enhance the action of insulin and influence lipid metabolism, potentially interacting with pathways involving LRCOL1.

Berberine

2086-83-1sc-507337
250 mg
$92.00
1
(0)

An alkaloid that has been shown to regulate enzymes involved in lipid metabolism, which could be indirectly influenced by LRCOL1's activity.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

A polyphenol that influences lipid and glucose metabolism enzymes, which may be part of the pathways LRCOL1 is involved in.