Gm1027 Activators
Chemical activators of the Gm1027 protein can facilitate its function through various mechanisms. Magnesium chloride supplies the magnesium ions essential for ATPase enzymes, which are crucial for the Gm1027 protein's ATP-dependent transport function. The presence of ATP itself is a fundamental activator, as it binds to the Gm1027 protein, providing the energy necessary for the conformational changes that drive its transport mechanism. Sodium orthovanadate serves as a phosphatase inhibitor, maintaining proteins in a phosphorylated state, which can be essential for the activation of the Gm1027 protein through secondary signaling pathways. Zinc sulfate contributes zinc ions, which may act as structural or regulatory cofactors, potentially enhancing the functional activity of Gm1027. Similarly, manganese chloride provides manganese ions, which might serve as crucial cofactors or act through initiating signaling pathways that activate the Gm1027 protein.
In addition to these cofactors and energy suppliers, other chemicals affect the Gm1027 protein by altering its structural environment. Dithiothreitol (DTT) can reduce disulfide bonds, potentially inducing a conformation conducive to Gm1027 activation. Ethanol and glycerol can integrate into lipid bilayers, affecting membrane fluidity and potentially facilitating the necessary conformational changes in the Gm1027 protein. S-Nitroso-N-acetylpenicillamine (SNAP) acts as a nitric oxide donor, which can lead to post-translational modifications such as S-nitrosylation, affecting the Gm1027 protein's conformation or its interaction with other molecules. Calcium chloride provides calcium ions, which are key in intracellular signaling cascades that can lead to the activation of the Gm1027 protein. Lastly, nucleotides like UTP and GTP can engage with specific receptors or G-proteins, triggering signaling pathways that ultimately promote the Gm1027 protein's transport activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
Magnesium ions are essential cofactors for ATPase enzymes. Since the Gm1027 protein is an ABC transporter, which requires ATP hydrolysis to activate transport, magnesium chloride can provide the necessary ions to facilitate this reaction, thereby directly enabling the activation of the Gm1027 protein's transport function. | ||||||
ADP | 58-64-0 | sc-507362 | 5 g | $53.00 | ||
ATP binds directly to the nucleotide-binding domain of the Gm1027 protein, providing the energy for the conformational changes that are essential for its transport mechanism. This direct binding is a primary method of activation for the Gm1027 protein, as it is an ABC transporter. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $45.00 $56.00 $183.00 | 142 | |
Sodium orthovanadate acts as a phosphatase inhibitor. By preventing dephosphorylation, it can sustain the phosphorylated state of proteins involved in signaling pathways that regulate the activity of the Gm1027 protein, leading to its activation. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc ions can act as structural or regulatory cofactors for many proteins, including transporters. The presence of zinc sulfate can provide these ions, potentially enabling or enhancing the functional activity of the Gm1027 protein. | ||||||
Glycerol | 56-81-5 | sc-29095A sc-29095 | 100 ml 1 L | $55.00 $150.00 | 12 | |
By integrating into the lipid bilayer, glycerol can affect the membrane's physical state. This can influence the activity of membrane proteins like the Gm1027 protein by easing the conformational shifts required for its activation. | ||||||
(±)-S-Nitroso-N-acetylpenicillamine | 79032-48-7 | sc-200319B sc-200319 sc-200319A | 10 mg 20 mg 100 mg | $73.00 $112.00 $367.00 | 18 | |
As a nitric oxide donor, SNAP can induce post-translational modifications such as S-nitrosylation. Such modifications can activate the Gm1027 protein by changing its conformation or by altering interactions with other proteins or substrates, thus leading to activation of its function. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $30.00 | ||
Manganese ions can serve as essential cofactors for various enzymes and proteins. Their presence can activate the Gm1027 protein by serving as a cofactor that is necessary for the protein’s function or by initiating signaling pathways that lead to the protein's activation. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $65.00 $262.00 | 1 | |
Calcium ions play a pivotal role in intracellular signaling. Calcium chloride can provide these ions, which can activate signaling pathways that, in turn, lead to the functional activation of the Gm1027 protein. | ||||||
Guanosine-5′-Triphosphate, Disodium salt | 86-01-1 | sc-507564 | 1 g | $700.00 | ||
GTP binds to and activates G-proteins, which are involved in numerous signaling pathways. Such pathways can lead to the activation of the Gm1027 protein by facilitating the conformational changes or protein-protein interactions required for its transport function. | ||||||