GLP-1 (Glucagon-Like Peptide-1) activators belong to a distinctive chemical class that plays a crucial role in regulating blood glucose levels and metabolism within the human body. GLP-1 is a natural hormone secreted by the intestinal cells in response to food consumption, particularly in the presence of carbohydrates. This hormone's primary function is to stimulate the release of insulin from pancreatic beta cells, which subsequently facilitates the uptake of glucose by cells, leading to lowered blood sugar levels. GLP-1 activators, also known as GLP-1 receptor agonists, are synthetic compounds designed to mimic the action of endogenous GLP-1, amplifying its effects and offering benefits for individuals with conditions related to glucose regulation.
These activators interact with specific receptors on pancreatic beta cells and other target tissues, initiating a cascade of intracellular events that culminate in enhanced insulin secretion. Additionally, GLP-1 activators slow down gastric emptying, leading to a reduction in appetite and food intake, which can contribute to weight loss. Furthermore, they suppress glucagon release, a hormone responsible for raising blood sugar levels, further aiding in glucose control. GLP-1 activators have gained attention in the medical field due to their to help manage conditions such as type 2 diabetes and obesity. Their ability to mimic the natural functions of GLP-1 makes them an intriguing area of research.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Liraglutide | 204656-20-2 | sc-507404 | 1 mg | $220.00 | ||
GLP-1 receptor agonist; enhances GLP-1 receptor activity. | ||||||
Exendin-4 | 141758-74-9 | sc-474611 sc-474611A | 500 µg 1 mg | $146.00 $198.00 | 1 | |
GLP-1 receptor agonist; mimics the action of GLP-1. | ||||||
Nateglinide | 105816-04-4 | sc-394067 sc-394067A | 10 mg 25 mg | $192.00 $265.00 | ||
Increases GLP-1 secretion by pancreatic cells. | ||||||
Sitagliptin | 486460-32-6 | sc-482298 sc-482298A sc-482298B | 25 mg 100 mg 1 g | $213.00 $473.00 $733.00 | 10 | |
DPP-4 inhibitor; prolongs the half-life of endogenous GLP-1. | ||||||