Date published: 2025-12-8

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GLP-1R Antibodies

Santa Cruz Biotechnology provides a broad selection of GLP-1R monoclonal antibodies for research focused on understanding the glucagon-like peptide-1 receptor. Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The GLP-1 receptor plays a crucial role in glucose metabolism and insulin secretion, making it a significant target in diabetes research and therapeutic development. By mediating the effects of GLP-1, the receptor influences appetite regulation and promotes β-cell function, highlighting its importance in metabolic health. Research into GLP-1R mechanisms continues to advance understanding of type 2 diabetes and obesity. Scientists worldwide utilize GLP-1R monoclonal antibodies to explore receptor function, distribution, and regulation across different tissue types. Investigating GLP-1R signaling pathways provides insights into potential therapeutic strategies for metabolic disorders. GLP-1R monoclonal antibodies from Santa Cruz Biotechnology enable researchers to make meaningful contributions to metabolic disease research and therapeutic development.

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GLP-1R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GLP-1R Antibody (D-6)

sc-390774mouse IgG2a κ91-145 (h)WB, IP, IF, ELISAm, r, h
27
(6)

GLP-1R Antibody (B-11)

sc-390773mouse IgG2b κ91-145 (h)WB, IP, IF, ELISAm, r, h
13
(2)

GLP-1R CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GLP-1R CRISPR/Cas9 KO Plasmid (h)

sc-400847hGene KnockoutGFP0
(0)

GLP-1R HDR Plasmid (h)

sc-400847-HDRhHomology Directed RepairPuromycin0
(0)

GLP-1R Double Nickase Plasmid (h)

sc-400847-NIChGene KnockoutPuromycin0
(0)

GLP-1R Double Nickase Plasmid (h2)

sc-400847-NIC-2hGene KnockoutPuromycin0
(0)

GLP-1R CRISPR/Cas9 KO Plasmid (m)

sc-420581mGene KnockoutGFP0
(0)

GLP-1R HDR Plasmid (m)

sc-420581-HDRmHomology Directed RepairPuromycin0
(0)

GLP-1R Double Nickase Plasmid (m)

sc-420581-NICmGene KnockoutPuromycin0
(0)

GLP-1R Double Nickase Plasmid (m2)

sc-420581-NIC-2mGene KnockoutPuromycin0
(0)

GLP-1R CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GLP-1R CRISPR Activation Plasmid (h)

sc-400847-ACThGene ActivationPuro, Blast, Hygro0
(0)

GLP-1R CRISPR Activation Plasmid (h2)

sc-400847-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GLP-1R Lentiviral Activation Particles (h)

sc-400847-LAChGene ActivationPuro, Blast, Hygro0
(0)

GLP-1R Lentiviral Activation Particles (h2)

sc-400847-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GLP-1R CRISPR Activation Plasmid (m)

sc-420581-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GLP-1R CRISPR Activation Plasmid (m2)

sc-420581-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GLP-1R Lentiviral Activation Particles (m)

sc-420581-LACmGene ActivationPuro, Blast, Hygro0
(0)

GLP-1R Lentiviral Activation Particles (m2)

sc-420581-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GLP-1R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GLP-1R siRNA (h)

sc-45760hGene SilencingN/A
2
(0)

GLP-1R shRNA Plasmid (h)

sc-45760-SHhGene SilencingPuromycin
2
(0)

GLP-1R shRNA (h) Lentiviral Particles

sc-45760-VhGene SilencingPuromycin
2
(0)

GLP-1R siRNA (m)

sc-45764mGene SilencingN/A
1
(0)

GLP-1R shRNA Plasmid (m)

sc-45764-SHmGene SilencingPuromycin
1
(0)

GLP-1R shRNA (m) Lentiviral Particles

sc-45764-VmGene SilencingPuromycin
1
(0)

GLP-1R siRNA (r)

sc-270026rGene SilencingN/A
1
(0)

GLP-1R shRNA Plasmid (r)

sc-270026-SHrGene SilencingPuromycin
1
(0)

GLP-1R shRNA (r) Lentiviral Particles

sc-270026-VrGene SilencingPuromycin
1
(0)