Date published: 2026-4-1

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GDPD3 Activators

GDPD3 activators are a diverse array of chemical compounds that interact with and enhance the functional activity of GDPD3 by influencing specific lipid signaling pathways and cellular processes. For instance, phosphatidic acid can supply the substrate that GDPD3 may act upon, leading to the production of diacylglycerol, a potent secondary messenger that is instrumental in the signaling processes GDPD3 participates in. Similarly, sphingosine-1-phosphate and ceramide traverse the lipid signaling cascade, which can indirectly result in the enhancement of GDPD3 activity by modulating the levels of lipid mediators within the cell. The inclusion of lysophosphatidic acid and diacylglycerol among the activators further underscores the pivotal role these lipids play in GDPD3-associated pathways, where they can amplify the signaling potential of GDPD3 by altering the lipid signaling milieu.

The functional activity of GDPD3 is intricately connected to the dynamics of cellular lipid composition and metabolism. Arachidonic acid, a polyunsaturated fatty acid, can be metabolized into various bioactive lipids that engage in GDPD3-related pathways, thereby heightening its activity. The secondary messenger IP3 releases calcium, which can interact with GDPD3.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Phosphatidic Acid, Dipalmitoyl

169051-60-9sc-201057
sc-201057B
sc-201057A
100 mg
250 mg
500 mg
$106.00
$244.00
$417.00
(1)

As GDPD3 is involved in lipid signaling, phosphatidic acid could enhance GDPD3 activity by providing substrate that can be dephosphorylated, which may result in the production of diacylglycerol (DAG), a secondary messenger that promotes cellular signaling processes GDPD3 is involved in.

D-erythro-Sphingosine-1-phosphate

26993-30-6sc-201383
sc-201383D
sc-201383A
sc-201383B
sc-201383C
1 mg
2 mg
5 mg
10 mg
25 mg
$165.00
$322.00
$570.00
$907.00
$1727.00
7
(1)

S1P is a lipid signaling molecule that can engage signaling cascades GDPD3 is a part of, potentially leading to its functional activation through altered lipid signaling dynamics.

Lysophosphatidic Acid

325465-93-8sc-201053
sc-201053A
5 mg
25 mg
$98.00
$341.00
50
(3)

LPA is a bioactive lipid that can modulate several signaling pathways, including those associated with GDPD3, potentially leading to an increase in its activity.

Arachidonic Acid (20:4, n-6)

506-32-1sc-200770
sc-200770A
sc-200770B
100 mg
1 g
25 g
$92.00
$240.00
$4328.00
9
(1)

As a fatty acid, arachidonic acid can be integrated into cellular membranes and upon release can be converted into active lipid mediators that are involved in GDPD3 signaling pathways, enhancing its activity.

NAD+, Free Acid

53-84-9sc-208084B
sc-208084
sc-208084A
sc-208084C
sc-208084D
sc-208084E
sc-208084F
1 g
5 g
10 g
25 g
100 g
1 kg
5 kg
$57.00
$191.00
$302.00
$450.00
$1800.00
$3570.00
$10710.00
4
(2)

NAD+, as a substrate for ADP-ribosylation, may influence signaling pathways involving GDPD3, indirectly leading to its activation.

Adenosine 5′-Triphosphate, disodium salt

987-65-5sc-202040
sc-202040A
1 g
5 g
$39.00
$75.00
9
(1)

ATP can serve as a substrate for kinases that phosphorylate proteins in signaling pathways associated with GDPD3, possibly enhancing its activity.